We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Grading of MRI-detected skull-base invasion in nasopharyngeal carcinoma and its prognostic value.
- Authors
Chen, Lei; Liu, Li-Zhi; Mao, Yan-Ping; Tang, Ling-Long; Sun, Ying; Chen, Yong; Lin, Ai-Hua; Li, Li; Ma, Jun
- Abstract
Background. Our aim was to grade MRI-detected skull-base invasion in nasopharyngeal carcinoma and evaluate the prognostic value of the grading. Methods. The MRI scans and medical records of 924 patients with histologically diagnosed nondisseminated nasopharyngeal carcinoma were reviewed retrospectively. Results. MRI-detected skull-base invasion was not found to be an independent prognostic factor for overall survival, distant metastasis-free survival, or local relapse-free survival ( p > .05 for all). Grading of skull-base erosion according to the site of invasion was found to be an independent prognostic factor for both overall survival ( p = .003 and p = .006, respectively) and distant metastasis-free survival ( p = .001 for both) in the 512 patients with skull-base invasions and 315 patients with T3 disease. Conclusions. MRI-detected skull-base invasion is not an independent prognostic factor for nasopharyngeal carcinoma. However, grading according to the site of invasion as either low grade or severe has prognostic value. © 2010 Wiley Periodicals, Inc. Head Neck, 2010
- Subjects
MAGNETIC resonance imaging; MEDICAL records; SKULL base; METASTASIS; PROGNOSTIC tests; NASOPHARYNX diseases; RETROSPECTIVE studies
- Publication
Head & Neck, 2011, Vol 33, Issue 9, p1309
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.21606