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Mechanisms of 8‐aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model.
Published in:
Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 13, p. 3675, doi. 10.1111/jcmm.17362
By:
- Flaherty, Siobhan;
- Strauch, Pamela;
- Maktabi, Mahdi;
- Pybus, Brandon S.;
- Reichard, Gregory;
- Walker, Larry A;
- Rochford, Rosemary
Publication type:
Article
Pre-clinical evaluation of CYP 2D6 dependent drug–drug interactions between primaquine and SSRI/SNRI antidepressants.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1329-z
By:
- Xiannu Jin;
- Brittney Potter;
- Thu-lan Luong;
- Nelson, Jennifer;
- Chau Vuong;
- Potter, Corttney;
- Lisa Xie;
- Jing Zhang;
- Ping Zhang;
- Sousa, Jason;
- Qigui Li;
- Pybus, Brandon S.;
- Kreishman-Deitrick, Mara;
- Hickman, Mark;
- Smith, Philip L.;
- Paris, Robert;
- Reichard, Gregory;
- Marcsisin, Sean R.
Publication type:
Article
Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1270-1
By:
- Fasinu, Pius S.;
- Avula, Bharathi;
- Tekwani, Babu L.;
- Nanayakkara, N. P. Dhammika;
- Yan-Hong Wang;
- Herath, H. M. T. Bandara;
- McChesney, James D.;
- Reichard, Gregory A.;
- Marcsisin, Sean R.;
- Elsohly, Mahmoud A.;
- Khan, Shabana I.;
- Khan, Ikhlas A.;
- Walker, Larry A.
Publication type:
Article
Isolation of circulating metabolites in drug discovery using high-performance liquid chromatography, and their identification by liquid chromatography coupled with tandem mass spectrometry and nuclear magnetic resonance spectroscopy.
Published in:
Journal of Separation Science, 2002, v. 25, n. 14, p. 877, doi. 10.1002/1615-9314(20021001)25:14<877::AID-JSSC877>3.0.CO;2-W
By:
- Kim, Hong;
- Feng, Wenqing;
- Chan, Tze-Ming;
- Rindgen, Diane;
- Bryant, Matthew;
- Cox, Kathleen A.;
- Xia, Yan;
- Reichard, Gregory;
- Paliwal, Sunil;
- Hesk, David;
- Palamanda, Jairam;
- White, Ronald E.;
- Nomeir, Amin A.
Publication type:
Article
Development of an ectopic huLiver model for Plasmodium liver stage infection.
Published in:
PLoS ONE, 2023, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0279144
By:
- Samayoa-Reyes, Gabriela;
- Flaherty, Siobhan M.;
- Wickham, Kristina S.;
- Viera-Morilla, Sara;
- Strauch, Pamela M.;
- Roth, Alison;
- Padrón, Laura;
- Jackson, Conner M.;
- Meireles, Patricia;
- Calvo, David;
- Roobsoong, Wanlapa;
- Kangwanrangsan, Niwat;
- Sattabongkot, Jetsumon;
- Reichard, Gregory;
- Lafuente-Monasterio, Maria José;
- Rochford, Rosemary
Publication type:
Article
Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
Published in:
Journal of Infectious Diseases, 2020, v. 221, n. 7, p. 1204, doi. 10.1093/infdis/jiz599
By:
- Spring, Michele D;
- Sousa, Jason C;
- Li, Qigui;
- Darko, Christian A;
- Morrison, Meshell N;
- Marcsisin, Sean R;
- Mills, Kristin T;
- Potter, Brittney M;
- Paolino, Kristopher M;
- Twomey, Patrick S;
- Moon, James E;
- Tosh, Donna M;
- Cicatelli, Susan B;
- Froude, Jeffrey W;
- Pybus, Brandon S;
- Oliver, Thomas G;
- Mccarthy, William F;
- Waters, Norman C;
- Smith, Philip L;
- Reichard, Gregory A
Publication type:
Article
Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
Published in:
2020
By:
- Spring, Michele D;
- Sousa, Jason C;
- Li, Qigui;
- Darko, Christian A;
- Morrison, Meshell N;
- Marcsisin, Sean R;
- Mills, Kristin T;
- Potter, Brittney M;
- Paolino, Kristopher M;
- Twomey, Patrick S;
- Moon, James E;
- Tosh, Donna M;
- Cicatelli, Susan B;
- Froude, Jeffrey W;
- Pybus, Brandon S;
- Oliver, Thomas G;
- Mccarthy, William F;
- Waters, Norman C;
- Smith, Philip L;
- Reichard, Gregory A
Publication type:
journal article
Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
Published in:
2019
By:
- Spring, Michele D;
- Sousa, Jason C;
- Li, Qigui;
- Darko, Christian A;
- Morrison, Meshell N;
- Marcsisin, Sean R;
- Mills, Kristin T;
- Potter, Brittney M;
- Paolino, Kristopher M;
- Twomey, Patrick S;
- Moon, James E;
- Tosh, Donna M;
- Cicatelli, Susan B;
- Froude, Jeffrey W;
- Pybus, Brandon S;
- Oliver, Thomas G;
- McCarthy, William F;
- Waters, Norman C;
- Smith, Philip L;
- Reichard, Gregory A
Publication type:
journal article
Enantioselective metabolism of primaquine by human CYP2D6.
Published in:
Malaria Journal, 2014, v. 13, n. 1, p. 686, doi. 10.1186/1475-2875-13-507
By:
- Fasinu, Pius S.;
- Tekwani, Babu L.;
- Dhammika Nanayakkara, N. P.;
- Avula, Bharathi;
- Bandara Herath, H. M. T.;
- Yan-Hong Wang;
- Adelli, Vijender R.;
- Elsohly, Mahmoud A.;
- Khan, Shabana I.;
- Khan, Ikhlas A.;
- Pybus, Brandon S.;
- Marcsisin, Sean R.;
- Reichard, Gregory A.;
- McChesney, James D.;
- Walker, Larry A.
Publication type:
Article
Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.
Published in:
Malaria Journal, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2875-13-2
By:
- Marcsisin, Sean R.;
- Sousa, Jason C.;
- Reichard, Gregory A.;
- Caridha, Diana;
- Qiang Zeng;
- Roncal, Norma;
- McNulty, Ronan;
- Careagabarja, Julio;
- Sciotti, Richard;
- Bennett, Jason W.;
- Zottig, Victor E.;
- Deye, Gregory;
- Qigui Li;
- Read, Lisa;
- Hickman, Mark;
- Nanayakkara, Dhammika;
- Walker, Larry A.;
- Smith, Bryan;
- Melendez, Victor;
- Pybus, Brandon S.
Publication type:
Article
The metabolism of primaquine to its active metabolite is dependent on CYP 2D6.
Published in:
Malaria Journal, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2875-12-212
By:
- Pybus, Brandon S.;
- Marcsisin, Sean R.;
- Jin, Xiannu;
- Deye, Gregory;
- Sousa, Jason C.;
- Qigui Li;
- Diana Caridha;
- Qiang Zeng;
- Reichard, Gregory A.;
- Ockenhouse, Christian;
- Bennett, Jason;
- Walker, Larry A.;
- Ohrt, Colin;
- Melendez, Victor
Publication type:
Article
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.
Published in:
Malaria Journal, 2012, v. 11, n. 1, p. 259, doi. 10.1186/1475-2875-11-259
By:
- Pybus, Brandon S.;
- Sousa, Jason C.;
- Xiannu Jin;
- Ferguson, James A.;
- Christian, Robert E.;
- Barnhart, Rebecca;
- Chau Vuong;
- Sciotti, Richard J.;
- Reichard, Gregory A.;
- Kozar, Michael P.;
- Walker, Larry A.;
- Ohrt, Colin;
- Melendez, Victor
Publication type:
Article
Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria.
Published in:
Malaria Journal, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12936-019-2661-x
By:
- Caridha, Diana;
- Hickman, Mark;
- Xie, Lisa;
- Ngundam, Franklyn;
- Milner, Erin;
- Schenk, Amanda;
- Butler, Kirk;
- Nugent, Dylan;
- Lee, Patricia;
- Roncal, Norma;
- Leed, Susan;
- Hosford, Eve;
- Lee, Jangwoo;
- Sciotti, Richard J.;
- Reichard, Gregory;
- Black, Chad;
- Kreishman-Deitrick, Mara;
- Li, Qigui;
- Vesely, Brian
Publication type:
Article

Found: 13