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- Title
Adipose Tissue Regeneration: A State of the Art.
- Authors
Casadei, Alessandro; Epis, Roberta; Ferroni, Letizia; Tocco, Ilaria; Gardin, Chiara; Bressan, Eriberto; Sivolella, Stefano; Vindigni, Vincenzo; Pinton, Paolo; Mucci, Giuseppe; Zavan, Barbara
- Abstract
Adipose tissue pathologies and defects have always represented a reconstructive challenge for plastic surgeons. In more recent years, several allogenic and alloplastic materials have been developed and used as fillers for soft tissue defects. However, their clinical use has been limited by further documented complications, such as foreign-body reactions potentially affecting function, degradation over time, and the risk for immunogenicity. Tissue-engineering strategies are thus being investigated to develop methods for generating adipose tissue. This paper will discuss the current state of the art in adipose tissue engineering techniques, exploring the biomaterials used, stem cells application, culture strategies, and current regulatory framework that are in use are here described and discussed.
- Subjects
ADIPOSE tissues; BIOMEDICAL materials; POLYMERS; REGENERATION (Biology); STEM cells; TISSUE engineering
- Publication
Journal of Biomedicine & Biotechnology, 2012, Vol 2012, p1
- ISSN
1110-7243
- Publication type
Article
- DOI
10.1155/2012/462543