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Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01181-y
By:
- Peikert, Kevin;
- Federti, Enrica;
- Matte, Alessandro;
- Constantin, Gabriela;
- Pietronigro, Enrica Caterina;
- Fabene, Paolo Francesco;
- Defilippi, Paola;
- Turco, Emilia;
- Del Gallo, Federico;
- Pucci, Pietro;
- Amoresano, Angela;
- Illiano, Anna;
- Cozzolino, Flora;
- Monti, Maria;
- Garello, Francesca;
- Terreno, Enzo;
- Alper, Seth Leo;
- Glaß, Hannes;
- Pelzl, Lisann;
- Akgün, Katja
Publication type:
Article
Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders.
Published in:
Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00212
By:
- Alfieri, Annalisa;
- Sorokina, Oksana;
- Adrait, Annie;
- Angelini, Costanza;
- Russo, Isabella;
- Morellato, Alessandro;
- Matteoli, Michela;
- Menna, Elisabetta;
- Erba, Elisabetta Boeri;
- McLean, Colin;
- Armstrong, J. Douglas;
- Ala, Ugo;
- Buxbaum, Joseph D.;
- Brusco, Alfredo;
- Couté, Yohann;
- De Rubeis, Silvia;
- Turco, Emilia;
- Defilippi, Paola
Publication type:
Article
Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival.
Published in:
EMBO Journal, 1998, v. 17, n. 22, p. 6622, doi. 10.1093/emboj/17.22.6622
By:
- Moro, Laura;
- Venturino, Mascia;
- Bozzo, Chiarella;
- Silengo, Lorenzo;
- Altruda, Fiorella;
- Beguinot, Laura;
- Tarone, Guido;
- Defilippi, Paola
Publication type:
Article
The winding road from adhesive receptors to the nucleus.
Published in:
2002
By:
- Defilippi, Paola;
- Vallés, Ana M.
Publication type:
Report
The role of tumor microenvironment in drug resistance: emerging technologies to unravel breast cancer heterogeneity.
Published in:
Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1170264
By:
- Salemme, Vincenzo;
- Centonze, Giorgia;
- Avalle, Lidia;
- Natalini, Dora;
- Piccolantonio, Alessio;
- Arina, Pietro;
- Morellato, Alessandro;
- Ala, Ugo;
- Taverna, Daniela;
- Turco, Emilia;
- Defilippi, Paola
Publication type:
Article
p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity.
Published in:
Stem Cells, 2013, v. 31, n. 7, p. 1422, doi. 10.1002/stem.1403
By:
- Tornillo, Giusy;
- Elia, Angela Rita;
- Castellano, Isabella;
- Spadaro, Michela;
- Bernabei, Paola;
- Bisaro, Brigitte;
- Camacho-Leal, Maria del Pilar;
- Pincini, Alessandra;
- Provero, Paolo;
- Sapino, Anna;
- Turco, Emilia;
- Defilippi, Paola;
- Cabodi, Sara
Publication type:
Article
β1 integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation.
Published in:
Journal of Cell Biology, 2005, v. 168, n. 7, p. 1099, doi. 10.1083/jcb.200405116
By:
- Defilippi, Paola;
- Rosso, Arturo;
- Dentelli, Patrizia;
- Calvi, Cristina;
- Garbarino, Giovanni;
- Tarone, Guido;
- Pegoraro, Luigi;
- Brizzi, Maria Felice
Publication type:
Article
Mapping of p140Cap Phosphorylation Sites: The EPLYA and EGLYA Motifs Have a Key Role in Tyrosine Phosphorylation and Csk Binding, and Are Substrates of the Abl Kinase.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054931
By:
- Repetto, Daniele;
- Aramu, Simona;
- Erba, Elisabetta Boeri;
- Sharma, Nanaocha;
- Grasso, Silvia;
- Russo, Isabella;
- Jensen, Ole N.;
- Cabodi, Sara;
- Turco, Emilia;
- Di Stefano, Paola;
- Defilippi, Paola
Publication type:
Article
p130Cas Over-Expression Impairs Mammary Branching Morphogenesis in Response to Estrogen and EGF.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0049817
By:
- del Pilar Camacho Leal, Maria;
- Pincini, Alessandra;
- Tornillo, Giusy;
- Fiorito, Elisa;
- Bisaro, Brigitte;
- Di Luca, Elisa;
- Turco, Emilia;
- Defilippi, Paola;
- Cabodi, Sara
Publication type:
Article
The interaction between KDR and interleukin-3 receptor (IL-3R) beta common modulates tumor neovascularization.
Published in:
Oncogene, 2005, v. 24, n. 42, p. 6394, doi. 10.1038/sj.onc.1208786
By:
- Dentelli, Patrizia;
- Rosso, Arturo;
- Garbarino, Giovanni;
- Calvi, Cristina;
- Lombard, Emanuela;
- Di Stefano, Paola;
- Defilippi, Paola;
- Pegoraro, Luigi;
- Brizzi, Maria Felice
Publication type:
Article
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11510-4
By:
- Costa, Tânia D. F.;
- Olofsson, Helene;
- Masia-Balague, Miriam;
- Rabieifar, Parisa;
- Spiess, Matthias;
- Hernández-Varas, Pablo;
- Rabenhorst, Uta;
- Gong, Xiaowei;
- Strömblad, Staffan;
- Zhuang, Ting;
- Zhao, Miao;
- Lorent, Julie;
- Ma, Ran;
- Hartman, Johan;
- Turco, Emilia;
- Defilippi, Paola;
- Robertson, Neil;
- Adams, Peter D.;
- Kuiper, Raoul;
- Sjölund, Jonas
Publication type:
Article
p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.
Published in:
EMBO Journal, 2007, v. 26, n. 12, p. 2843, doi. 10.1038/sj.emboj.7601724
By:
- Di Stefano, Paola;
- Damiano, Laura;
- Cabodi, Sara;
- Aramu, Simona;
- Tordella, Luca;
- Praduroux, Alice;
- Piva, Roberto;
- Cavallo, Federica;
- Forni, Guido;
- Silengo, Lorenzo;
- Tarone, Guido;
- Turco, Emilia;
- Defilippi, Paola
Publication type:
Article
Author Correction: Modeling ErbB2-p130Cas interaction to design new potential anticancer agents.
Published in:
2019
By:
- Costamagna, Andrea;
- Rossi Sebastiano, Matteo;
- Natalini, Dora;
- Simoni, Matilde;
- Valabrega, Giorgio;
- Defilippi, Paola;
- Visentin, Sonja;
- Ermondi, Giuseppe;
- Turco, Emilia;
- Caron, Giulia;
- Cabodi, Sara
Publication type:
Correction Notice
The Crosstalk Between Tumor Cells and the Immune Microenvironment in Breast Cancer: Implications for Immunotherapy.
Published in:
Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.610303
By:
- Salemme, Vincenzo;
- Centonze, Giorgia;
- Cavallo, Federica;
- Defilippi, Paola;
- Conti, Laura
Publication type:
Article
Distinct involvement of Cdc42 and RhoA GTPases in actin organization and cell shape in untransformed and Dbl oncogene transformed NIH3T3 cells.
Published in:
Oncogene, 2000, v. 19, n. 11, p. 1428, doi. 10.1038/sj.onc.1203440
By:
- Olivo, Cristina;
- Vanni, Cristina;
- Mancini, Patrizia;
- Silengo, Lorenzo;
- Torrisi, Maria Rosaria;
- Tarone, Guido;
- Defilippi, Paola;
- Eva, Alessandra
Publication type:
Article
Actin cytoskeleton polymerization in Dbl-transformed NIH3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins.
Published in:
Oncogene, 1997, v. 14, n. 16, p. 1933, doi. 10.1038/sj.onc.1201027
By:
- Defilippi, Paola;
- Olivo, Cristina;
- Tarone, Guido;
- Mancini, Patrizia;
- Torrisi, Maria Rosaria;
- Eva, Alessandra
Publication type:
Article
Cas proteins: dodgy scaffolding in breast cancer.
Published in:
2014
By:
- Tornillo, Giusy;
- Defilippi, Paola;
- Cabodi, Sara
Publication type:
journal article
p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells.
Published in:
Breast Cancer Research, 2012, v. 14, n. 5, p. 3342, doi. 10.1186/bcr3342
By:
- Bisaro, Brigitte;
- Montani, Maura;
- Konstantinidou, Georgia;
- Marchini, Cristina;
- Pietrella, Lucia;
- Iezzi, Manuela;
- Galiè, Mirco;
- Orso, Francesca;
- Camporeale, Annalisa;
- Colombo, Shana M.;
- Di Stefano, Paola;
- Tornillo, Giusy;
- Camacho-Leal, Maria P.;
- Turco, Emilia;
- Taverna, Daniela;
- Cabodi, Sara;
- Amici, Augusto;
- Defilippi, Paola
Publication type:
Article
p130Cas/Cyclooxygenase-2 axis in the control of mesenchymal plasticity of breast cancer cells.
Published in:
2012
By:
- Bisaro, Brigitte;
- Montani, Maura;
- Konstantinidou, Georgia;
- Marchini, Cristina;
- Pietrella, Lucia;
- Iezzi, Manuela;
- Galiè, Mirco;
- Orso, Francesca;
- Camporeale, Annalisa;
- Colombo, Shana M;
- Di Stefano, Paola;
- Tornillo, Giusy;
- Camacho-Leal, Maria P;
- Turco, Emilia;
- Taverna, Daniela;
- Cabodi, Sara;
- Amici, Augusto;
- Defilippi, Paola
Publication type:
journal article
miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression.
Published in:
Cellular & Molecular Life Sciences, 2022, v. 79, n. 4, p. 1, doi. 10.1007/s00018-022-04228-y
By:
- Quirico, Lorena;
- Orso, Francesca;
- Cucinelli, Stefania;
- Paradzik, Mladen;
- Natalini, Dora;
- Centonze, Giorgia;
- Dalmasso, Alberto;
- La Vecchia, Sofia;
- Coco, Martina;
- Audrito, Valentina;
- Riganti, Chiara;
- Defilippi, Paola;
- Taverna, Daniela
Publication type:
Article
The p140Cap adaptor protein as a molecular hub to block cancer aggressiveness.
Published in:
Cellular & Molecular Life Sciences, 2021, v. 78, n. 4, p. 1355, doi. 10.1007/s00018-020-03666-w
By:
- Salemme, Vincenzo;
- Angelini, Costanza;
- Chapelle, Jennifer;
- Centonze, Giorgia;
- Natalini, Dora;
- Morellato, Alessandro;
- Taverna, Daniela;
- Turco, Emilia;
- Ala, Ugo;
- Defilippi, Paola
Publication type:
Article
p130Cas is an essential transducer element in ErbB2 transformation.
Published in:
FASEB Journal, 2010, v. 24, n. 10, p. 3796, doi. 10.1096/fj.10-157347
By:
- Cabodi, Sara;
- Tinnirello, Agata;
- Bisaro, Brigitte;
- Tornillo, Giusy;
- Camacho-Leal, Maria del Pilar;
- Forni, Guido;
- Cojoca, Rodica;
- Iezzi, Manuela;
- Amici, Augusto;
- Montani, Maura;
- Eva, Alessandra;
- Di Stefano, Paola;
- Muthuswamy, Senthil K.;
- Tarone, Guido;
- Turco, Emilia;
- Defilippi, Paola
Publication type:
Article
SNAP-25 regulates spine formation through postsynaptic binding to p140Cap.
Published in:
Nature Communications, 2013, v. 4, n. 7, p. 2136, doi. 10.1038/ncomms3136
By:
- Tomasoni, Romana;
- Repetto, Daniele;
- Morini, Raffaella;
- Elia, Chiara;
- Gardoni, Fabrizio;
- Di Luca, Monica;
- Turco, Emilia;
- Defilippi, Paola;
- Matteoli, Michela
Publication type:
Article
Actin cytoskeleton organization in response to integrin-mediated adhesion.
Published in:
Microscopy Research & Technique, 1999, v. 47, n. 1, p. 67, doi. 10.1002/(SICI)1097-0029(19991001)47:1<67::AID-JEMT7>3.0.CO;2-P
By:
- Defilippi, Paola;
- Olivo, Cristina;
- Venturino, Mascia;
- Dolce, Laura;
- Silengo, Lorenzo;
- Tarone, Guido
Publication type:
Article
STAT5 activation induced by diabetic LDL depends on LDL glycation and occurs via src kinase activity.
Published in:
2002
By:
- Brizzi, Maria Felice;
- Dentelli, Patrizia;
- Gambino, Roberto;
- Cabodi, Sara;
- Cassader, Maurizio;
- Castelli, Ada;
- Defilippi, Paola;
- Pegoraro, Luigi;
- Pagano, Gianfranco
Publication type:
journal article
Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression.
Published in:
Journal of Cellular Physiology, 2009, v. 218, n. 2, p. 294, doi. 10.1002/jcp.21603
By:
- Cabodi, Sara;
- Morello, Virginia;
- Masi, Alessio;
- Cicchi, Riccardo;
- Broggio, Chiara;
- DiStefano, Paola;
- Brunelli, Elisa;
- Silengo, Lorenzo;
- Pavone, Francesco;
- Arcangeli, Annarosa;
- Turco, Emilia;
- Tarone, Guido;
- Moro, Laura;
- Defilippi, Paola
Publication type:
Article
Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2‐neo mouse rescued by L‐type calcium channel blockers.
Published in:
Journal of Physiology, 2019, v. 597, n. 6, p. 1705, doi. 10.1113/JP277487
By:
- Calorio, Chiara;
- Gavello, Daniela;
- Guarina, Laura;
- Salio, Chiara;
- Sassoè‐Pognetto, Marco;
- Riganti, Chiara;
- Bianchi, Federico Tommaso;
- Hofer, Nadja T.;
- Tuluc, Petronel;
- Obermair, Gerald J.;
- Defilippi, Paola;
- Balzac, Fiorella;
- Turco, Emilia;
- Bett, Glenna C.;
- Rasmusson, Randall L.;
- Carbone, Emilio
Publication type:
Article
Road to metastasis: alternative mRNA translation regulates Triple-Negative Breast Cancer bioenergetics.
Published in:
Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2022, v. 126, p. 252
By:
- Falletta, Paola;
- Gaviraghi, Marco;
- Loffreda, Alessia;
- Crippa, Martina;
- Salemme, Vincenzo;
- Chauhan, Jagat;
- Goding, Colin;
- Defilippi, Paola;
- Tacchetti, Carlo
Publication type:
Article
Triple negative-breast cancer translation rewiring shapes invasiveness and niche composition.
Published in:
Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2021, v. 125, p. 64
By:
- Falletta, Paola;
- Chauhan, Jagat;
- Salemme, Vincenzo;
- Licari, Eugenia;
- Sarcinella, Alessandro;
- Gaviraghi, Marco;
- Loffreda, Alessia;
- Daniele, Tiziana;
- Defilippi, Paola;
- Tacchetti, Carlo
Publication type:
Article
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis.
Published in:
Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-016-0385-8
By:
- Principe, Moitza;
- Borgoni, Simone;
- Cascione, Mariafrancesca;
- Chattaragada, Michelle Samuel;
- Ferri-Borgogno, Sammy;
- Capello, Michela;
- Bulfamante, Sara;
- Chapelle, Jennifer;
- Di Modugno, Francesca;
- Defilippi, Paola;
- Nisticò, Paola;
- Cappello, Paola;
- Riganti, Chiara;
- Leporatti, Stefano;
- Novelli, Francesco
Publication type:
Article
p140Cap Regulates the Composition and Localization of the NMDAR Complex in Synaptic Lipid Rafts.
Published in:
Journal of Neuroscience, 2022, v. 42, n. 38, p. 7183, doi. 10.1523/JNEUROSCI.1775-21.2022
By:
- Angelini, Costanza;
- Morellato, Alessandro;
- Alfieri, Annalisa;
- Pavinato, Lisa;
- Cravero, Tiziana;
- Bianciotto, Olga Teresa;
- Salemme, Vincenzo;
- Natalini, Dora;
- Centonze, Giorgia;
- Raspanti, Alessandra;
- Garofalo, Tina;
- Valdembri, Donatella;
- Serini, Guido;
- Marcantoni, Andrea;
- Becchetti, Andrea;
- Giustetto, Maurizio;
- Turco, Emilia;
- Defilippi, Paola
Publication type:
Article
Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration.
Published in:
Journal of Neuroscience, 2019, v. 39, n. 29, p. 5634, doi. 10.1523/JNEUROSCI.0024-19.2019
By:
- Calipari, Erin S.;
- Godino, Arthur;
- Salery, Marine;
- Damez-Werno, Diane M.;
- Cahill, Michael E.;
- Werner, Craig T.;
- Gancarz, Amy M.;
- Peck, Emily G.;
- Jlayer, Zahra;
- Rabkin, Jacqui;
- Landry, Joseph A.;
- Smith, Alexander C. W.;
- Defilippi, Paola;
- Kenny, Paul J.;
- Hurd, Yasmin L.;
- Neve, Rachael L.;
- Dietz, David M.;
- Nestler, Eric J.
Publication type:
Article
Molecular Insights into the MAPK Cascade during Viral Infection: Potential Crosstalk between HCQ and HCQ Analogues.
Published in:
BioMed Research International, 2020, p. 1, doi. 10.1155/2020/8827752
By:
- Mohanta, Tapan Kumar;
- Sharma, Nanaocha;
- Arina, Pietro;
- Defilippi, Paola
Publication type:
Article
Modeling ErbB2-p130Cas interaction to design new potential anticancer agents.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39510-w
By:
- Costamagna, Andrea;
- Rossi Sebastiano, Matteo;
- Natalini, Dora;
- Simoni, Matilde;
- Valabrega, Giorgio;
- Defilippi, Paola;
- Visentin, Sonja;
- Ermondi, Giuseppe;
- Turco, Emilia;
- Caron, Giulia;
- Cabodi, Sara
Publication type:
Article
Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.
Published in:
Journal of Neurochemistry, 2008, v. 107, n. 1, p. 61, doi. 10.1111/j.1471-4159.2008.05585.x
By:
- Ito, Hidenori;
- Atsuzawa, Kimie;
- Sudo, Kaori;
- Di Stefano, Paola;
- Iwamoto, Ikuko;
- Morishita, Rika;
- Takei, Shiro;
- Semba, Reiji;
- Defilippi, Paola;
- Asano, Tomiko;
- Usuda, Nobuteru;
- Nagata, Koh-ichi
Publication type:
Article
Association of the Dystroglycan Complex Isolated from Bovine Brain Synaptosomes with Proteins Involved in Signal Transduction.
Published in:
Journal of Neurochemistry, 1999, v. 72, n. 4, p. 1648, doi. 10.1046/j.1471-4159.1999.721648.x
By:
- Cavaldesi, Michaela;
- Macchia, Gianfranco;
- Barca, Stefano;
- Defilippi, Paola;
- Tarone, Guido;
- Petrucci, Tamara C.
Publication type:
Article
Correction to: Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation.
Published in:
2018
By:
- del Pilar Camacho Leal, Maria;
- Costamagna, Andrea;
- Tassone, Beatrice;
- Saoncella, Stefania;
- Simoni, Matilde;
- Natalini, Dora;
- Dadone, Aurora;
- Sciortino, Marianna;
- Turco, Emilia;
- Defilippi, Paola;
- Calautti, Enzo;
- Cabodi, Sara
Publication type:
Correction Notice
Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation.
Published in:
Cell Communication & Signaling, 2018, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12964-018-0289-z
By:
- Camacho Leal, Maria del Pilar;
- Costamagna, Andrea;
- Tassone, Beatrice;
- Saoncella, Stefania;
- Simoni, Matilde;
- Natalini, Dora;
- Dadone, Aurora;
- Sciortino, Marianna;
- Turco, Emilia;
- Defilippi, Paola;
- Calautti, Vincenzo;
- Cabodi, Sara
Publication type:
Article
Integrin signalling adaptors: not only figurants in the cancer story.
Published in:
2010
By:
- Cabodi, Sara;
- del Pilar Camacho-Leal, Maria;
- Di Stefano, Paola;
- Defilippi, Paola
Publication type:
journal article
p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons.
Published in:
Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.744693
By:
- Camera, Mattia;
- Russo, Isabella;
- Zamboni, Valentina;
- Ammoni, Alessandra;
- Rando, Simona;
- Morellato, Alessandro;
- Cimino, Irene;
- Angelini, Costanza;
- Giacobini, Paolo;
- Oleari, Roberto;
- Amoruso, Federica;
- Cariboni, Anna;
- Franceschini, Isabelle;
- Turco, Emilia;
- Defilippi, Paola;
- Merlo, Giorgio R.
Publication type:
Article
p140Cap Regulates Memory and Synaptic Plasticity through Src-Mediated and Citron-N-Mediated Actin Reorganization.
Published in:
Journal of Neuroscience, 2014, v. 34, n. 4, p. 1542, doi. 10.1523/JNEUROSCI.2341-13.2014
By:
- Repetto, Daniele;
- Camera, Paola;
- Melani, Riccardo;
- Morello, Noemi;
- Russo, Isabella;
- Calcagno, Eleonora;
- Tomasoni, Romana;
- Bianchi, Federico;
- Berto, Gaia;
- Giustetto, Maurizio;
- Berardi, Nicoletta;
- Pizzorusso, Tommaso;
- Matteoli, Michela;
- Di Stefano, Paola;
- Missler, Markus;
- Turco, Emilia;
- Di Cunto, Ferdinando;
- Defilippi, Paola
Publication type:
Article

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