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- Title
Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19).
- Authors
Anderson, Elizabeth M; Diorio, Caroline; Goodwin, Eileen C; McNerney, Kevin O; Weirick, Madison E; Gouma, Sigrid; Bolton, Marcus J; Arevalo, Claudia P; Chase, Julie; Hicks, Philip; Manzoni, Tomaz B; Baxter, Amy E; Andrea, Kurt P; Burudpakdee, Chakkapong; Lee, Jessica H; Vella, Laura A; Henrickson, Sarah E; Harris, Rebecca M; Wherry, E John; Bates, Paul
- Abstract
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibody responses in children remain poorly characterized. Here, we show that pediatric patients with multisystem inflammatory syndrome in children (MIS-C) possess higher SARS-CoV-2 spike immunoglobulin G (IgG) titers compared with those with severe coronavirus disease 2019, likely reflecting a longer time since the onset of infection in MIS-C patients.
- Subjects
IMMUNOGLOBULINS; COVID-19; SYSTEMIC inflammatory response syndrome; MULTIPLE organ failure; PEDIATRICS; SARS disease
- Publication
Journal of the Pediatric Infectious Diseases Society, 2021, Vol 10, Issue 5, p669
- ISSN
2048-7193
- Publication type
Article
- DOI
10.1093/jpids/piaa161