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- Title
Applications of extraembryonic tissue-derived cells in vascular tissue regeneration.
- Authors
Goushki, Mehdi Amiri; Kharat, Zahra; Kehtari, Mousa; Sohi, Alireza Naderi; Ahvaz, Hana Hanaee; Rad, Iman; HosseinZadeh, Simzar; Kouhkan, Fatemeh; Kabiri, Mahboubeh
- Abstract
Vascular tissue engineering is a promising approach for regenerating damaged blood vessels and developing new therapeutic approaches for heart disease treatment. To date, different sources of cells have been recognized that offer assistance within the recovery of heart supply routes and veins with distinctive capacities and are compelling for heart regeneration. However, some challenges still remain that need to be overcome to establish the full potential application of these cells. In this paper, we review the different cell sources used for vascular tissue engineering, focusing on extraembryonic tissue-derived cells (ESCs), and elucidate their roles in cardiovascular disease. In addition, we highlight the intricate interplay between mechanical and biochemical factors in regulating mesenchymal stem cell (MSC) differentiation, offering insights into optimizing their application in vascular tissues.
- Subjects
REGENERATION (Biology); CARDIAC regeneration; MESENCHYMAL stem cells; TISSUE engineering; TISSUES; HEART
- Publication
Stem Cell Research & Therapy, 2024, Vol 15, Issue 1, p1
- ISSN
1757-6512
- Publication type
Article
- DOI
10.1186/s13287-024-03784-3