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- Title
Is it time to use real-world data from primary care in Alzheimer's disease?
- Authors
Ponjoan, Anna; Garre-Olmo, Josep; Blanch, Jordi; Fages, Ester; Alves-Cabratosa, Lia; Martí-Lluch, Ruth; Comas-Cufí, Marc; Parramon, Dídac; Garcia-Gil, María; Ramos, Rafel
- Abstract
Background: The analysis of real-world data in clinical research is rising, but its use to study dementia subtypes has been hardly addressed. We hypothesized that real-world data might be a powerful tool to update AD epidemiology at a lower cost than face-to-face studies, to estimate the prevalence and incidence rates of AD in Catalonia (Southern Europe), and to assess the adequacy of real-world data routinely collected in primary care settings for epidemiological research on AD. Methods: We obtained data from the System for the Development of Research in Primary Care (SIDIAP) database, which contains anonymized information of > 80% of the Catalan population. We estimated crude and standardized incidence rates and prevalences (95% confidence intervals (CI)) of AD in people aged at least 65 years living in Catalonia in 2016. Results: Age- and sex-standardized prevalence and incidence rate of AD were 3.1% (95%CI 2.7–3.6) and 4.2 per 1000 person-years (95%CI 3.8–4.6), respectively. Prevalence and incidence were higher in women and in the oldest people. Conclusions: Our incidence and prevalence estimations were slightly lower than the recent face-to-face studies conducted in Spain and higher than other analyses of electronic health data from other European populations. Real-world data routinely collected in primary care settings could be a powerful tool to study the epidemiology of AD.
- Subjects
CATALONIA (Spain); SPAIN; ALZHEIMER'S disease; PRIMARY care; TIME management; OLDER people; OLDER women
- Publication
Alzheimer's Research & Therapy, 2020, Vol 12, Issue 1, p1
- ISSN
1758-9193
- Publication type
Article
- DOI
10.1186/s13195-020-00625-2