We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Molecular determination of epidermal growth factor receptor in normal and neoplastic colorectal mucosa.
- Authors
Piazzi, G.; Paterini, P.; Ceccarelli, C.; Pantaleo, M. A.; Biasco, G.
- Abstract
The epidermal growth factor receptor (EGFr) is considered a major target for treatment of colorectal cancer (CRC). We found a mean EGFr content significantly lower but more activated in colonic neoplastic tissue than in paired normal mucosa. Phosphorylated (pY1068) EGFr detection in CRC may be a better tool than EGFr detection to select patients for targeted therapies.British Journal of Cancer (2006) 95, 1525–1528. doi:10.1038/sj.bjc.6603441 www.bjcancer.com Published online 31 October 2006
- Subjects
COLON cancer; CANCER treatment; CANCER patients; GROWTH factors; MUCOUS membranes; CYTOKINES
- Publication
British Journal of Cancer, 2006, Vol 95, Issue 11, p1525
- ISSN
0007-0920
- Publication type
Article
- DOI
10.1038/sj.bjc.6603441