Found: 53
Select item for more details and to access through your institution.
Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development.
- Published in:
- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1150243
- By:
- Publication type:
- Article
Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development.
- Published in:
- Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1067295
- By:
- Publication type:
- Article
Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1063453
- By:
- Publication type:
- Article
Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 8, p. 1530, doi. 10.3390/pharmaceutics14081530
- By:
- Publication type:
- Article
Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 4, p. N.PAG, doi. 10.3390/pharmaceutics14040753
- By:
- Publication type:
- Article
Derivation and Clinical Utility of Safety Targets for Linezolid-Related Adverse Events in Drug-Resistant Tuberculosis Treatment.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 11, p. 1575, doi. 10.3390/ph16111575
- By:
- Publication type:
- Article
Risk Factors for COVID-19 and Respiratory Tract Infections during the Coronavirus Pandemic.
- Published in:
- Vaccines, 2024, v. 12, n. 3, p. 329, doi. 10.3390/vaccines12030329
- By:
- Publication type:
- Article
Cough as Noninvasive Biomarker for Monitoring Tuberculosis Treatment: A Proof-of-Concept Study.
- Published in:
- Annals of the American Thoracic Society, 2023, v. 20, n. 12, p. 1822, doi. 10.1513/annalsats.202305-456rl
- By:
- Publication type:
- Article
Comparisons of Analysis Methods for Assessment of Pharmacodynamic Interactions Including Design Recommendations.
- Published in:
- AAPS Journal, 2018, v. 20, n. 4, p. 1, doi. 10.1208/s12248-018-0239-0
- By:
- Publication type:
- Article
Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9.
- Published in:
- Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 1, p. 32, doi. 10.1016/S0009-9236(03)00092-4
- By:
- Publication type:
- Article
Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing—Using Rifampicin as an Example.
- Published in:
- Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00794
- By:
- Publication type:
- Article
Evaluation of critical parameters in the hollow‐fibre system for tuberculosis: A case study of moxifloxacin.
- Published in:
- British Journal of Clinical Pharmacology, 2024, v. 90, n. 7, p. 1711, doi. 10.1111/bcp.16068
- By:
- Publication type:
- Article
Population pharmacokinetics of edoxaban in patients with symptomatic deep-vein thrombosis and/or pulmonary embolism--the Hokusai-VTE phase 3 study.
- Published in:
- British Journal of Clinical Pharmacology, 2015, v. 80, n. 6, p. 1374, doi. 10.1111/bcp.12727
- By:
- Publication type:
- Article
Model-based approach to dose optimization of lopinavir/ritonavir when co-administered with rifampicin.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 73, n. 5, p. 758, doi. 10.1111/j.1365-2125.2011.04154.x
- By:
- Publication type:
- Article
Variability in the population pharmacokinetics of isoniazid in South African tuberculosis patients.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 72, n. 1, p. 51, doi. 10.1111/j.1365-2125.2011.03940.x
- By:
- Publication type:
- Article
Modelling of pain intensity and informative dropout in a dental pain model after naproxcinod, naproxen and placebo administration.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 6, p. 899, doi. 10.1111/j.1365-2125.2011.03924.x
- By:
- Publication type:
- Article
Model-Informed Drug Discovery and Development Strategy for the Rapid Development of Anti-Tuberculosis Drug Combinations.
- Published in:
- Applied Sciences (2076-3417), 2020, v. 10, n. 7, p. 2376, doi. 10.3390/app10072376
- By:
- Publication type:
- Article
Rifampicin Can Be Given as Flat-Dosing Instead of Weight-Band Dosing.
- Published in:
- Clinical Infectious Diseases, 2020, v. 71, n. 12, p. 3055, doi. 10.1093/cid/ciz1202
- By:
- Publication type:
- Article
Enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4′-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2006, v. 20, n. 4, p. 723, doi. 10.1002/rcm.2392
- By:
- Publication type:
- Article
Enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4′-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2006, v. 20, n. 3, p. 463, doi. 10.1002/rcm.2324
- By:
- Publication type:
- Article
The use of liquid chromatography/mass spectrometry for quantitative analysis of oxycodone, oxymorphone and noroxycodone in Ringer solution, rat plasma and rat brain tissue.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2004, v. 18, n. 21, p. 2565, doi. 10.1002/rcm.1658
- By:
- Publication type:
- Article
Subcutaneous Marzeptacog Alfa (Activated) for On‐Demand Treatment of Bleeding Events in Subjects With Hemophilia A or B With Inhibitors.
- Published in:
- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 3, p. 498, doi. 10.1002/cpt.3172
- By:
- Publication type:
- Article
A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses.
- Published in:
- Clinical Pharmacology & Therapeutics, 2018, v. 103, n. 4, p. 674, doi. 10.1002/cpt.778
- By:
- Publication type:
- Article
Population pharmacokinetics of nevirapine in combination with rifampicin-based short course chemotherapy in HIV- and tuberculosis-infected South African patients.
- Published in:
- European Journal of Clinical Pharmacology, 2009, v. 65, n. 1, p. 71, doi. 10.1007/s00228-008-0481-y
- By:
- Publication type:
- Article
Variability in the population pharmacokinetics of pyrazinamide in South African tuberculosis patients.
- Published in:
- European Journal of Clinical Pharmacology, 2006, v. 62, n. 9, p. 727, doi. 10.1007/s00228-006-0141-z
- By:
- Publication type:
- Article
Seasonal influence on respiratory tract infection severity including COVID‐19 quantified through Markov Chain modeling.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 9, p. 1250, doi. 10.1002/psp4.13006
- By:
- Publication type:
- Article
Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 7, p. 977, doi. 10.1002/psp4.12967
- By:
- Publication type:
- Article
Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1628, doi. 10.1002/psp4.12872
- By:
- Publication type:
- Article
Finding the right hazard function for time‐to‐event modeling: A tutorial and Shiny application.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 8, p. 991, doi. 10.1002/psp4.12797
- By:
- Publication type:
- Article
A modeling‐based proposal for safe and efficacious reintroduction of bedaquiline after dose interruption: A population pharmacokinetics study.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 5, p. 628, doi. 10.1002/psp4.12768
- By:
- Publication type:
- Article
Assessing Pharmacodynamic Interactions in Mice Using the Multistate Tuberculosis Pharmacometric and General Pharmacodynamic Interaction Models.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2017, v. 6, n. 11, p. 787, doi. 10.1002/psp4.12226
- By:
- Publication type:
- Article
Difference in persistent tuberculosis bacteria between in vitro and sputum from patients: implications for translational predictions.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-72472-y
- By:
- Publication type:
- Article
Population Pharmacokinetics of Edoxaban in Patients with Non-Valvular Atrial Fibrillation in the ENGAGE AF-TIMI 48 Study, a Phase III Clinical Trial.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Population pharmacokinetics of edoxaban and its main metabolite in a dedicated renal impairment study.
- Published in:
- Journal of Clinical Pharmacology, 2015, v. 55, n. 11, p. 1268, doi. 10.1002/jcph.541
- By:
- Publication type:
- Article
An Integrated Model for Glucose and Insulin Regulation in Healthy Volunteers and Type 2 Diabetic Patients Following Intravenous Glucose Provocations.
- Published in:
- Journal of Clinical Pharmacology, 2007, v. 47, n. 9, p. 1159, doi. 10.1177/0091270007304457
- By:
- Publication type:
- Article
Pharmacokinetics of Desmopressin Administrated as an Oral Lyophilisate Dosage Form in Children With Primary Nocturnal Enuresis and Healthy Adults.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 10, p. 1204, doi. 10.1177/0091270006291838
- By:
- Publication type:
- Article
A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 5, p. 421, doi. 10.1007/s10928-020-09694-0
- By:
- Publication type:
- Article
A two-compartment effect site model describes the bispectral index after different rates of propofol infusion.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2010, v. 37, n. 3, p. 243, doi. 10.1007/s10928-010-9157-1
- By:
- Publication type:
- Article
A general pharmacodynamic interaction model identifies perpetrators and victims in drug interactions.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01929-y
- By:
- Publication type:
- Article
Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects.
- Published in:
- Fundamental & Clinical Pharmacology, 2007, v. 21, n. 3, p. 307, doi. 10.1111/j.1472-8206.2007.00471.x
- By:
- Publication type:
- Article
Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene‐based FVIIa prophylaxis.
- Published in:
- Haemophilia, 2020, v. 26, n. 1, p. 164, doi. 10.1111/hae.13899
- By:
- Publication type:
- Article
Predictive Modeling to Study the Treatment-Shortening Potential of Novel Tuberculosis Drug Regimens, Toward Bundling of Preclinical Data.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Superior Efficacy of a Bedaquiline, Delamanid, and Linezolid Combination Regimen in a Mouse Tuberculosis Model.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients.
- Published in:
- Advances in Therapy, 2023, v. 40, n. 9, p. 3739, doi. 10.1007/s12325-023-02570-6
- By:
- Publication type:
- Article
Distribution of plasma concentrations of first-line anti-TB drugs and individual MICs: a prospective cohort study in a low endemic setting.
- Published in:
- 2018
- By:
- Publication type:
- journal article
A model-informed preclinical approach for prediction of clinical pharmacodynamic interactions of anti-TB drug combinations.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Improved power for TB Phase IIa trials using a model-based pharmacokinetic-pharmacodynamic approach compared with commonly used analysis methods.
- Published in:
- 2017
- By:
- Publication type:
- journal article
A multistate tuberculosis pharmacometric model: a framework for studying anti-tubercular drug effects in vitro.
- Published in:
- 2016
- By:
- Publication type:
- journal article