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- Title
Roles of interleukin-17 in uveitis.
- Authors
Esteves Guedes, Marta Catarina; Borrego, Luis Miguel; Proença, Rui Daniel; Guedes, Marta Catarina Esteves
- Abstract
Th17 cells, a CD4+ T-cell subset, produce interleukin (IL)-17, a pro-inflammatory cytokine that has been shown to be involved in several forms of infectious and noninfectious uveitis. Here, we explore the roles of this IL in uveitic disorders as well as in experimental autoimmune uveitis, the possible pathogenic implications of several cytokines associated with IL-17 and analyze the current outcomes and goals for drugs aiming for the IL-17 pathway.
- Subjects
UVEITIS; INTERLEUKIN-17; T helper cells; PHYSIOLOGICAL effects of cytokines; AUTOIMMUNITY; GENETICS; ANIMALS; AUTOIMMUNE diseases; BIOLOGICAL models; INTERLEUKINS; LYMPHOCYTES
- Publication
Indian Journal of Ophthalmology, 2016, Vol 64, Issue 9, p628
- ISSN
0301-4738
- Publication type
journal article
- DOI
10.4103/0301-4738.194339