Found: 10
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A phase Ib study to assess the efficacy and safety of vismodegib in combination with ruxolitinib in patients with intermediate- or high-risk myelofibrosis.
- Published in:
- 2018
- By:
- Publication type:
- Letter
Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies.
- Published in:
- Biopharmaceutics & Drug Disposition, 2012, v. 33, n. 2, p. 85, doi. 10.1002/bdd.1769
- By:
- Publication type:
- Article
UGT1A4 Polymorphism is not Associated with a Clinically Relevant Change in Giredestrant Exposure.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 1, p. 117, doi. 10.1007/s00280-023-04634-4
- By:
- Publication type:
- Article
Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 74, n. 5, p. 788, doi. 10.1111/j.1365-2125.2012.04281.x
- By:
- Publication type:
- Article
Cobimetinib Alone and Plus Venetoclax With/Without Atezolizumab in Patients With Relapsed/Refractory Multiple Myeloma.
- Published in:
- 2023
- By:
- Publication type:
- journal article
Single- and multiple-dose pharmacokinetics, potential for CYP3A inhibition, and food effect in patients with cancer and healthy subjects receiving ipatasertib.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2021, v. 88, n. 6, p. 921, doi. 10.1007/s00280-021-04344-9
- By:
- Publication type:
- Article
A clinical drug-drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 1, p. 193, doi. 10.1007/s00280-012-1996-6
- By:
- Publication type:
- Article
Pharmacokinetics of Ipatasertib in Subjects With Hepatic Impairment Using 2 Methods of Classification of Hepatic Function.
- Published in:
- Journal of Clinical Pharmacology, 2022, v. 62, n. 2, p. 171, doi. 10.1002/jcph.1941
- By:
- Publication type:
- Article
Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug‐induced heart rate changes.
- Published in:
- CTS: Clinical & Translational Science, 2023, v. 16, n. 5, p. 823, doi. 10.1111/cts.13491
- By:
- Publication type:
- Article