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- Title
Pre-treatment Emotional Distress in Patients Irradiated for Malignant Glioma.
- Authors
RADES, DIRK; AL-SALOOL, AHMED; YU, NATHAN Y.; TRILLENBERG, PETER; BONSANTO, MATTEO M.; LEPPERT, JAN
- Abstract
Background/Aim: A recommendation of radiotherapy for patients with malignant gliomas may trigger emotional distress. Frequency and risk factors of this complication were investigated. Patients and Methods: Prevalence of six emotional problems and 11 potential risk factors were evaluated in 103 patients irradiated for grade II-IV gliomas. p-Values <0.0045 were considered significant. Results: Seventy-six patients (74%) had =1 emotional problem. Prevalence of specific emotional problems ranged between 23% and 63%. Associations were found between =5 physical problems and worry (p=0.0010), fear (p=0.0001), sadness (p=0.0023), depression (p=0.0006), and loss of interest (p=0.0006), and Karnofsky performance score =80 and depression (p=0.0002). Trends were found for physical problems and nervousness (p=0.040), age =60 years and depression (p=0.043) or loss of interest (p=0.045), grade IV glioma and sadness (p=0.042), and =2 involved sites and loss of interest (p=0.022). Conclusion: Three-fourths of glioma patients had pre-radiotherapy emotional distress. Psychological support should be offered very soon, particularly for high-risk patients.
- Subjects
GLIOMAS; DISEASE risk factors; MENTAL depression; ANXIETY; IRRADIATION
- Publication
In Vivo, 2023, Vol 37, Issue 3, p1198
- ISSN
0258-851X
- Publication type
Article
- DOI
10.21873/invivo.13196