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- Title
Anti-Heparin Activity of a Macroglobulin from a Patient with Breast Adenocarcinoma.
- Authors
Pogliani, E.; Cofrancesco, E.; Praga, C.
- Abstract
We describe a case of IgM paraproteinemia, whose macroglobulin reacted anomalously with heparin. Anti-heparin activity of the paraprotein was suggested by insensibility of the patient's plasma to heparin in heparin-thrombin clotting time. Moreover, the presence of heparin in the medium markedly reduced the inhibitory effect of the paraprotein on platelet aggregation by ADP. Copyright © 1975 S. Karger AG, Basel
- Publication
Acta Haematologica, 1975, Vol 53, Issue 4, p249
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000208190