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- Title
Antibacterial triterpenoids from Melia toosendan.
- Authors
Qin Zhu; Ligen Lin; Chunping Tang; Changqiang Ke; Yang Ye
- Abstract
A new lanostan-type triterpenoid with hydroperoxy group, toosendanin A (1), together with two known triterpenoids, meliastatin 3 (2) and ursolic acid (3), were isolated and identified from the stems of Melia toosendan. The structures of these compounds were elucidated by 1D- and 2D-NMR spectra and other spectroscopic studies. These compounds were assayed for the antibacterial activities against some hospital pathogenic bacteria. Toosendanin A (1) exhibited strong antibacterial activity against K. pneumoniae.
- Subjects
ANTIBACTERIAL agents; TRITERPENOIDS; MELIACEAE; HYDROPEROXY radicals; URSOLIC acid; NUCLEAR magnetic resonance spectroscopy
- Publication
Records of Natural Products, 2015, Vol 9, Issue 2, p267
- ISSN
1307-6167
- Publication type
Article