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Hydrogen exchange mass spectrometry: what is it and what can it tell us?
Published in:
Analytical & Bioanalytical Chemistry, 2010, v. 397, n. 3, p. 967, doi. 10.1007/s00216-010-3556-4
By:
- Marcsisin, Sean R.;
- Engen, John R.
Publication type:
Article
Comparison of Anti-Xa Activity in Patients Receiving Apixaban or Rivaroxaban.
Published in:
2018
By:
- Bookstaver, David A.;
- Sparks, Kimberly;
- Pybus, Brandon S.;
- Davis, Dustin K.;
- Marcsisin, Sean R.;
- Sousa, Jason C.
Publication type:
journal article
Chemoprophylaxis Vaccination: Phase I Study to Explore Stage-specific Immunity to Plasmodium falciparum in US Adults.
Published in:
Clinical Infectious Diseases, 2020, v. 71, n. 6, p. 1481, doi. 10.1093/cid/ciz1010
By:
- Healy, Sara A;
- Murphy, Sean C;
- Hume, Jen C C;
- Shelton, Lisa;
- Kuntz, Steve;
- Voorhis, Wesley C Van;
- Moodie, Zoe;
- Metch, Barbara;
- Wang, Ruobing;
- Silver-Brace, Tiffany;
- Fishbaugher, Matthew;
- Kennedy, Mark;
- Finney, Olivia C;
- Chaturvedi, Richa;
- Marcsisin, Sean R;
- Hobbs, Charlotte V;
- Warner-Lubin, Margaret;
- Talley, Angela K;
- Wong-Madden, Sharon;
- Stuart, Ken
Publication type:
Article
Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1632-8
By:
- Milner, Erin E.;
- Berman, Jonathan;
- Caridha, Diana;
- Dickson, Samuel P.;
- Hickman, Mark;
- Lee, Patricia J.;
- Marcsisin, Sean R.;
- Read, Lisa T.;
- Roncal, Norma;
- Vesely, Brian A.;
- Xie, Lisa H.;
- Jing Zhang;
- Ping Zhang;
- Qigui Li
Publication type:
Article
Pre-clinical evaluation of CYP 2D6 dependent drug–drug interactions between primaquine and SSRI/SNRI antidepressants.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1329-z
By:
- Xiannu Jin;
- Brittney Potter;
- Thu-lan Luong;
- Nelson, Jennifer;
- Chau Vuong;
- Potter, Corttney;
- Lisa Xie;
- Jing Zhang;
- Ping Zhang;
- Sousa, Jason;
- Qigui Li;
- Pybus, Brandon S.;
- Kreishman-Deitrick, Mara;
- Hickman, Mark;
- Smith, Philip L.;
- Paris, Robert;
- Reichard, Gregory;
- Marcsisin, Sean R.
Publication type:
Article
Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1270-1
By:
- Fasinu, Pius S.;
- Avula, Bharathi;
- Tekwani, Babu L.;
- Nanayakkara, N. P. Dhammika;
- Yan-Hong Wang;
- Herath, H. M. T. Bandara;
- McChesney, James D.;
- Reichard, Gregory A.;
- Marcsisin, Sean R.;
- Elsohly, Mahmoud A.;
- Khan, Shabana I.;
- Khan, Ikhlas A.;
- Walker, Larry A.
Publication type:
Article
Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
Published in:
Journal of Infectious Diseases, 2020, v. 221, n. 7, p. 1204, doi. 10.1093/infdis/jiz599
By:
- Spring, Michele D;
- Sousa, Jason C;
- Li, Qigui;
- Darko, Christian A;
- Morrison, Meshell N;
- Marcsisin, Sean R;
- Mills, Kristin T;
- Potter, Brittney M;
- Paolino, Kristopher M;
- Twomey, Patrick S;
- Moon, James E;
- Tosh, Donna M;
- Cicatelli, Susan B;
- Froude, Jeffrey W;
- Pybus, Brandon S;
- Oliver, Thomas G;
- Mccarthy, William F;
- Waters, Norman C;
- Smith, Philip L;
- Reichard, Gregory A
Publication type:
Article
Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
Published in:
2020
By:
- Spring, Michele D;
- Sousa, Jason C;
- Li, Qigui;
- Darko, Christian A;
- Morrison, Meshell N;
- Marcsisin, Sean R;
- Mills, Kristin T;
- Potter, Brittney M;
- Paolino, Kristopher M;
- Twomey, Patrick S;
- Moon, James E;
- Tosh, Donna M;
- Cicatelli, Susan B;
- Froude, Jeffrey W;
- Pybus, Brandon S;
- Oliver, Thomas G;
- Mccarthy, William F;
- Waters, Norman C;
- Smith, Philip L;
- Reichard, Gregory A
Publication type:
journal article
Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
Published in:
2019
By:
- Spring, Michele D;
- Sousa, Jason C;
- Li, Qigui;
- Darko, Christian A;
- Morrison, Meshell N;
- Marcsisin, Sean R;
- Mills, Kristin T;
- Potter, Brittney M;
- Paolino, Kristopher M;
- Twomey, Patrick S;
- Moon, James E;
- Tosh, Donna M;
- Cicatelli, Susan B;
- Froude, Jeffrey W;
- Pybus, Brandon S;
- Oliver, Thomas G;
- McCarthy, William F;
- Waters, Norman C;
- Smith, Philip L;
- Reichard, Gregory A
Publication type:
journal article
A Randomized Trial Evaluating the Prophylactic Activity of DSM265 Against Preerythrocytic Plasmodium falciparum Infection During Controlled Human Malarial Infection by Mosquito Bites and Direct Venous Inoculation.
Published in:
2018
By:
- Murphy, Sean C.;
- Duke, Elizabeth R.;
- Shipman, Kelly J.;
- Jensen, Ryan L.;
- Youyi Fong;
- Ferguson, Sue;
- Janes, Holly E.;
- Gillespie, Kevin;
- Seilie, Annette M.;
- Hanron, Amelia E.;
- Rinn, Laurie;
- Fishbaugher, Matthew;
- VonGoedert, Tracie;
- Fritzen, Emma;
- Kappe, Stefan H.;
- Ming Chang;
- Sousa, Jason C.;
- Marcsisin, Sean R.;
- Chalon, Stephan;
- Duparc, Stephan
Publication type:
journal article
Enantioselective metabolism of primaquine by human CYP2D6.
Published in:
Malaria Journal, 2014, v. 13, n. 1, p. 686, doi. 10.1186/1475-2875-13-507
By:
- Fasinu, Pius S.;
- Tekwani, Babu L.;
- Dhammika Nanayakkara, N. P.;
- Avula, Bharathi;
- Bandara Herath, H. M. T.;
- Yan-Hong Wang;
- Adelli, Vijender R.;
- Elsohly, Mahmoud A.;
- Khan, Shabana I.;
- Khan, Ikhlas A.;
- Pybus, Brandon S.;
- Marcsisin, Sean R.;
- Reichard, Gregory A.;
- McChesney, James D.;
- Walker, Larry A.
Publication type:
Article
Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.
Published in:
Malaria Journal, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2875-13-2
By:
- Marcsisin, Sean R.;
- Sousa, Jason C.;
- Reichard, Gregory A.;
- Caridha, Diana;
- Qiang Zeng;
- Roncal, Norma;
- McNulty, Ronan;
- Careagabarja, Julio;
- Sciotti, Richard;
- Bennett, Jason W.;
- Zottig, Victor E.;
- Deye, Gregory;
- Qigui Li;
- Read, Lisa;
- Hickman, Mark;
- Nanayakkara, Dhammika;
- Walker, Larry A.;
- Smith, Bryan;
- Melendez, Victor;
- Pybus, Brandon S.
Publication type:
Article
CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever.
Published in:
Malaria Journal, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2875-12-214
By:
- Marcsisin, Sean R.;
- Xiannu Jin;
- Bettger, Theresa;
- McCulley, Nicholas;
- Sousa, Jason C.;
- Shanks, G. Dennis;
- Tekwani, Babu L.;
- Sahu, Rajnish;
- Reichard, Reichard;
- Sciotti, Richard J.;
- Melendez, Victor;
- Pybus, Brandon S.
Publication type:
Article
The metabolism of primaquine to its active metabolite is dependent on CYP 2D6.
Published in:
Malaria Journal, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2875-12-212
By:
- Pybus, Brandon S.;
- Marcsisin, Sean R.;
- Jin, Xiannu;
- Deye, Gregory;
- Sousa, Jason C.;
- Qigui Li;
- Diana Caridha;
- Qiang Zeng;
- Reichard, Gregory A.;
- Ockenhouse, Christian;
- Bennett, Jason;
- Walker, Larry A.;
- Ohrt, Colin;
- Melendez, Victor
Publication type:
Article
Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei.
Published in:
Population Health Metrics, 2016, v. 14, p. 1, doi. 10.1186/s12936-016-1632-8
By:
- Milner, Erin E.;
- Berman, Jonathan;
- Caridha, Diana;
- Dickson, Samuel P.;
- Hickman, Mark;
- Lee, Patricia J.;
- Marcsisin, Sean R.;
- Read, Lisa T.;
- Roncal, Norma;
- Vesely, Brian A.;
- Xie, Lisa H.;
- Jing Zhang;
- Ping Zhang;
- Qigui Li
Publication type:
Article

Found: 15