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- Title
Bone density in myelomeningocele: the effects of ambulatory status and other factors.
- Authors
Rosenstein, Byron D.; Greene, Walter B.; Herrington, Robert T.; Rosenstein, B D; Greene, W B; Herrington, R T; Blum, A S
- Abstract
Measurements were made of distal radius, mid-radius, tibia and metatarsal bone-density of 80 patients with myelomeningocele (17 thoracic, six L1/L2, 13 L3, 30 L4, 14 L5/sacral). For the upper extremity the bone density primarily was low in the thoracic patients, but in the tibia and metatarsal it showed a more linear correlation with neurological levels. The effect of age was highly significant at all sites; after controlling for this, the neurological level was a significant determinant of bone density at all sites, and this effect was greater in older children. Patients with impaired ambulation had decreased bone-density in the distal radius, tibia and metatarsal, but not in the mid-radius. Race had no significant effect on density after accounting for differences in neurological level. Weight for height and multiple fractures did not correlate with bone density. Although ambulatory status (weight-bearing stresses) and neurological status (muscle stresses) are both important factors in bone density, this study suggests that the latter is a more important determinant.
- Publication
Developmental Medicine & Child Neurology, 1987, Vol 29, Issue 4, p486
- ISSN
0012-1622
- Publication type
journal article
- DOI
10.1111/j.1469-8749.1987.tb02508.x