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- Title
Histopathology of human epilepsy.
- Authors
de Lanerolle, Nihal C.; Lee, Tih-shih; Spencer, Dennis D.
- Abstract
The histopathology of the hippocampus of patients with temporal lobe epilepsy shows two major processes. One involves reorganization of neural circuits in the dentate gyrus and the other a proliferation of reactive astrocytes that have many unusual properties. These modified astrocytes may play a major role in creating an epileptic focus. For an expanded treatment of this topic see Jasper's Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at ).
- Subjects
HISTOPATHOLOGY; EPILEPSY; NEUROGLIA; SEIZURES (Medicine); SPASMS
- Publication
Epilepsia (Series 4), 2010, Vol 51, p37
- ISSN
0013-9580
- Publication type
Article
- DOI
10.1111/j.1528-1167.2010.02823.x