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- Title
Micro-CT of carotid arteries: a tool for experimental studies.
- Authors
Mohr, Andreas; Wenke, Ruediger; Roemer, Frank W.; Lynch, John A.; Gatzka, Christian; Priebe, Markus; Guermazi, Ali; Grigorian, Mikayel; Heller, Martin; Mueller-Huelsbeck, Stefan
- Abstract
Micro-computed tomography (micro-CT) is a high-resolution, non-destructive tool for two- and three-dimensional imaging and quantification. The ability of this technique to assess atherosclerosis of the carotid artery was evaluated in three human cadaver samples based on the original axial acquisitions, multiplanar reconstructions and volume rendering techniques. Quantitative analysis included the calculation of: (1) the original lumen perimeter, original lumen area, plaque area, residual lumen area, calcified area and gross sectional area reduction of the vascular lumen from two-dimensional slices; (2) the total tissue volume, soft tissue volume and calcified tissue volume from the three-dimensional data set. This preliminary study demonstrates the potential of micro-CT as a supplementary method for the two- and three-dimensional ex vivo evaluation of carotid atherosclerosis.
- Subjects
ATHEROSCLEROSIS; MEDICAL radiography; TOMOGRAPHY; ARTERIES; ARTERIAL diseases; MEDICAL imaging systems; DIAGNOSIS
- Publication
CardioVascular & Interventional Radiology, 2004, Vol 27, Issue 6, p651
- ISSN
0174-1551
- Publication type
journal article
- DOI
10.1007/s00270-003-0128-4