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- Title
Feline thyroid carcinoma: diagnosis and response to high-dose radioactive iodine treatment
- Authors
Hibbert, Angie; Gruffydd-Jones, Tim; Barrett, Esther L.; Day, Michael J.; Harvey, Andrea M.
- Abstract
This study reports the scintigraphy, histopathology, sole treatment with high-dose radioactive iodine and outcome of eight cases of feline thyroid carcinoma. Scintigraphic findings were variable and in 7/8 cases scintigraphic features could not reliably distinguish whether the thyroid tissue was malignant. Histopathology revealed typical criteria of malignancy in all cases, with mitotic activity described most frequently (7/8 cases), followed by infiltration of local tissues (4/8 cases). Cellular pleomorphism was infrequently observed. Single high-dose (1100MBq I131) radioiodine therapy was successful in 6/8 cases, with complete resolution of hyperthyroidism, and was associated with prolonged survival times (181–2381 days). Sole treatment with high-dose radioiodine is a safe and effective treatment for functional thyroid carcinoma. The prognosis for feline thyroid carcinoma successfully treated with radioiodine is good, with extended survival times commonly achieved.
- Subjects
THYROID cancer diagnosis; CAT diseases; THERAPEUTIC use of iodine isotopes; CANCER treatment; HISTOPATHOLOGY; RADIONUCLIDE imaging; DRUG dosage
- Publication
Journal of Feline Medicine & Surgery, 2009, Vol 11, Issue 2, p116
- ISSN
1098-612X
- Publication type
Article
- DOI
10.1016/j.jfms.2008.02.010