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- Title
Flat-detector computed tomography in the assessment of intracranial stents: comparison with multi detector CT and conventional angiography in a new animal model.
- Authors
Struffert T; Ott S; Adamek E; Schwarz M; Engelhorn T; Kloska S; Deuerling-Zheng Y; Doerfler A; Struffert, Tobias; Ott, Sabine; Adamek, Edyta; Schwarz, Marc; Engelhorn, Tobias; Kloska, Stephan; Deuerling-Zheng, Yu; Doerfler, Arnd
- Abstract
<bold>Objective: </bold>Careful follow up is necessary after intracranial stenting because in-stent restenosis (ISR) or residual stenosis (RS) is not rare. A minimally invasive follow-up imaging technique is desirable. The objective was to compare the visualisation of stents in Flat Detector-CT Angiography (FD-CTA) after intravenous contrast medium injection (i.v.) with Multi Detector Computed Tomography Angiography (MD-CTA) and Digital Subtracted Angiography (DSA) in an animal model.<bold>Methods: </bold>Stents were implanted in the carotid artery of 12 rabbits. In 6 a residual stenosis (RS) was surgically created. Imaging was performed using FD-CTA, MD-CTA and DSA. Measurements of the inner and outer diameter and cross-section area of the stents were performed. Stenosis grade was calculated.<bold>Results: </bold>In subjective evaluation FD-CTA was superior to MD-CTA. FD-CTA was more accurate compared with DSA than MD-CTA. Cross-sectional area of the stent lumen was significantly larger (p < 0.05) in FD-CTA in comparison to MD-CTA. Accurate evaluation of stenosis was impossible in MD-CTA. There was no statistically significant difference in the stenosis grade of DSA and FD-CTA.<bold>Conclusion: </bold>Our results show that visualisation of stent and stenosis using intravenous FD-CTA compares favourably with DSA and may replace DSA in the follow-up of patients treated with intracranial stents.
- Subjects
ANIMAL experimentation; CEREBRAL angiography; COMPUTED tomography; DIGITAL subtraction angiography; DIGITAL image processing; NONPARAMETRIC statistics; RABBITS; SURGICAL stents; CONTRAST media; DRUG administration; DRUG dosage
- Publication
European Radiology, 2011, Vol 21, Issue 8, p1779
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-011-2093-7