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- Title
Contribution to the histoenzymatic changes in multiple sclerosis.
- Authors
Wender, M.; Kozik, M.
- Abstract
The activities of acP, alkP, ATP-ase, TPP-ase, non-specific esterase, ASS, AChE and ChE have been investigated by histochemical methods, in the brain of 2 cases of multiple sclerosis. A decrease in the activity of ASS, AChE, ChE and alkP was noticed in the demyelinated white matter of the plaques. Inside the plaques also a loss of ChE activity in the oligodendroglia was observed, whereas the activity of ATP-ase, TPP-ase and acP was increased. The significance of the changes found of the neuroglia hyperactivity in demyelination is discussed.
- Publication
Acta Neuropathologica, 1969, Vol 13, Issue 2, p143
- ISSN
0001-6322
- Publication type
Article
- DOI
10.1007/BF00687026