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- Title
Cultures of equine respiratory epithelial cells and organ explants as tools for the study of equine influenza virus infection.
- Authors
Lin, C.; Holland Jr, R. E.; Williams, N. M.; Chambers, T. M.
- Abstract
Summary. Equine nasal turbinate epithelial cells and tracheal rafts were maintained with sustained viability in culture. Both types of culture supported productive replication of equine influenza virus (equine-2, subtype H3N8) and cell death occurred through apoptosis following viral infection. Thus, primary respiratory epithelial cell and organ cultures of equine origin may be valuable as alternatives to the intact animal for studying the virus-host interaction of equine respiratory viruses including influenza.
- Subjects
HORSE diseases; INFLUENZA viruses; EQUINE influenza; EPITHELIAL cells; CELL culture; RESPIRATORY infections
- Publication
Archives of Virology, 2001, Vol 146, Issue 11, p2239
- ISSN
0304-8608
- Publication type
Article
- DOI
10.1007/s007050170034