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- Title
Ph1 Locus Suppresses Cdk2-Type Activity during Premeiosis and Meiosis in Wheat.
- Authors
Greer, Emma; Martín, Azahara C.; Pendle, Ali; Colas, Isabelle; Jones, Alexandra M.E.; Moore, Graham; Shaw, Peter
- Abstract
Despite possessing multiple sets of related (homoeologous) chromosomes, hexaploid wheat (Triticum aestivum) restricts pairing to just true homologs at meiosis. Deletion of a single major locus, Pairing homoeologous1 (Ph1), allows pairing of homoeologs. How can the same chromosomes be processed as homologs instead of being treated as nonhomologs? Ph1 was recently defined to a cluster of defective cyclin-dependent kinase (Cdk)-like genes showing some similarity to mammalian Cdk2. We reasoned that the cluster might suppress Cdk2-type activity and therefore affect replication and histone H1 phosphorylation. Our study does indeed reveal such effects, suggesting that Cdk2-type phosphorylation has a major role in determining chromosome specificity during meiosis.
- Subjects
MEIOSIS; CHROMOSOMES; CYCLIN-dependent kinases; PHOSPHORYLATION
- Publication
Plant Cell, 2012, Vol 24, Issue 1, p152
- ISSN
1040-4651
- Publication type
Article
- DOI
10.1105/tpc.111.094771