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- Title
Baseline characteristics of participants in the Kerala Diabetes Prevention Program: a cluster randomized controlled trial of lifestyle intervention in Asian Indians.
- Authors
Sathish, T.; Oldenburg, B.; Tapp, R. J.; Shaw, J. E.; Wolfe, R.; Sajitha, B.; D'Esposito, F.; Absetz, P.; Mathews, E.; Zimmet, P. Z.; Thankappan, K. R.
- Abstract
Aims To describe the baseline characteristics of participants in the Kerala Diabetes Prevention Program. Methods The Kerala Diabetes Prevention Program is a cluster randomized controlled trial of lifestyle intervention for prevention of Type 2 diabetes mellitus in India. Participants in the study were those aged 30-60 years who had an Indian Diabetes Risk Score ≥ 60 and who were without Type 2 diabetes on oral glucose tolerance test. Data on demographic, lifestyle, clinical and biochemical characteristics were collected using standardized tools. Results A total of 2586 individuals were screened with the Indian Diabetes Risk Score, of these 1529 people (59.1%) had a score ≥ 60, of whom 1209 (79.1%) underwent an oral glucose tolerance test. A total of 202 individuals (16.7%) had undiagnosed Type 2 diabetes and were excluded, and the remaining 1007 individuals were enrolled in the trial (control arm, n = 507; intervention arm, n = 500). The mean participant age was 46.0 ± 7.5 years, and 47.2% were women. The mean Indian Diabetes Risk Score was 67.1 ± 8.4. More than two-thirds (69.0%) had prediabetes and 31.0% had normal glucose tolerance. The prevalence of cardiometabolic risk factors was high, including current tobacco use (34.4% in men), current alcohol use (39.3% in men), no leisure time exercise (98.0%), no daily intake of fruit and vegetables (78.7%), family history of diabetes (47.9%), overweight or obesity (68.5%), hypertension (22.3%) and dyslipidemia (85.4%). Conclusions The Kerala Diabetes Prevention Program recruited participants using a diabetes risk score. A large proportion of the participants had prediabetes and there were high rates of cardiometabolic risk factors. The trial will evaluate the effectiveness of lifestyle intervention in a population selected on the basis of a diabetes risk score.
- Subjects
INDIA; DIABETES risk factors; TYPE 2 diabetes prevention; ASIANS; BEHAVIOR modification; ALCOHOL drinking; FOOD habits; GLUCOSE tolerance tests; HEALTH behavior; HYPERLIPIDEMIA; HYPERTENSION; OBESITY; PREDIABETIC state; RISK assessment; SCALE analysis (Psychology); SMOKING; SOCIOECONOMIC factors; RANDOMIZED controlled trials; FAMILY history (Medicine); SEDENTARY lifestyles; EVALUATION of human services programs; DESCRIPTIVE statistics; CLUSTER sampling
- Publication
Diabetic Medicine, 2017, Vol 34, Issue 5, p647
- ISSN
0742-3071
- Publication type
Article
- DOI
10.1111/dme.13165