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- Title
Receptor-like kinase complexes in plant innate immunity.
- Authors
Greeff, Christiaan; Roux, Milena; Mundy, John; Petersen, Morten
- Abstract
Receptor-like kinases (RLKs) are surface localized, transmembrane receptors comprising a large family of well-studied kinases. RLKs signal through their transmembrane and juxtamembrane domains with the aid of various interacting partners and downstream components. The N-terminal extracellular domain defines ligand specificity, and RLK families are sub-classed according to this domain. The most studied of these subfamilies include those with (1) leucine-rich repeat (LRR) domains, (2) LysM domains (LYM), and (3) the Catharanthus roseus RLK1-like (CrRLK1L) domain. These proteins recognize distinct ligands of microbial origin or ligands derived from intracellular protein/carbohydrate signals. For example, the pattern-recognition receptor (PRR) AtFLS2 recognizes flg22 from flagellin, and the PRR AtEFR recognizes elf18 from elongation factor (EF-Tu). Upon binding of their cognate ligands, the aforementioned RLKs activate generic immune responses termed pattern-triggered immunity (PTI). RLKs can form complexes with other family members and engage a variety of intracellular signaling components and regulatory pathways upon stimulation. This review focuses on interesting new data about how these receptors form protein complexes to exert their function.
- Subjects
RECEPTOR-like kinases; IMMUNITY; PLANTS; LIGANDS (Biochemistry); LIGAND binding (Biochemistry); EXTRACELLULAR matrix proteins
- Publication
Frontiers in Plant Science, 2012, Vol 3, p1
- ISSN
1664-462X
- Publication type
Article
- DOI
10.3389/fpls.2012.00209