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- Title
Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry.
- Authors
Seung Jin Han; Kyung-Soo Kim; Wonjin Kim; Jung Hee Kim; Yong-ho Lee; Ji Sun Nam; Ji A Seo; Bu Kyung Kim; Jihyun Lee; Jin Ook Chung; Min-Hee Kim; Tae-Seo Sohn; Han Seok Choi; Seong Bin Hong; Yoon-Sok Chung
- Abstract
Background: The aim of this study was to investigate the prevalence of obesity in Korean men with Klinefelter syndrome (KS) and the associated risk factors for obesity and hyperglycemia. Methods: Data were collected retrospectively from medical records from 11 university hospitals in Korea between 1994 and 2014. Subjects aged ≥18 years with newly diagnosed KS were enrolled. The following parameters were recorded at baseline before treatment: chief complaint, height, weight, fasting glucose level, lipid panel, blood pressure, testosterone, luteinizing hormone, folliclestimulating hormone, karyotyping patterns, and history of hypertension, diabetes, and dyslipidemia. Results: Data were analyzed from 376 of 544 initially enrolled patients. The rate of the 47 XXY chromosomal pattern was 94.1%. The prevalence of obesity (body mass index ≥25 kg/m2) in Korean men with KS was 42.6%. The testosterone level was an independent risk factor for obesity and hyperglycemia. Conclusion: Obesity is common in Korean men with KS. Hypogonadism in patients with KS was associated with obesity and hyperglycemia.
- Subjects
KOREA; HYPERGLYCEMIA; KLINEFELTER'S syndrome; PATIENTS
- Publication
Endocrinology & Metabolism, 2016, Vol 31, Issue 4, p598
- ISSN
2093-596X
- Publication type
Article
- DOI
10.3803/EnM.2016.31.4.598