We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Lessons of the month 2: Olanzapine-induced hypothermia and hand oedema.
- Authors
Camilleri, Doriella; Fiorini, Anthony
- Abstract
Introduction We describe a case of olanzapine-induced hypothermia and hand oedema in an older adult with behavioural and psychological symptoms of dementia (BPSD). Case presentation An 82-year-old woman with hypothyroidism and dementia was reviewed by the geriatric team at a nursing home in view of lethargy and an unrecordable oral temperature. She was noted to have a bilateral hand oedema and right basal crackles. Investigations revealed high white cell count and inflammatory markers. She was treated as per hypothermia and community-acquired pneumonia protocols. The patient did not have the expected response to treatment. Olanzapine was tailed down and stopped with good effect as it was suspected to be a contributory cause to both the hypothermia and oedema. Discussion and conclusion Potentially inappropriate polypharmacy can be specifically targeted with effective deprescribing. Treatment review should be encouraged on a regular basis, especially in frail older adults with polypharmacy.
- Subjects
DEPRESCRIBING; ARM; OLANZAPINE; HYPOTHERMIA; TERMINATION of treatment; EDEMA
- Publication
Clinical Medicine, 2022, Vol 22, Issue 3, p285
- ISSN
1470-2118
- Publication type
Article
- DOI
10.7861/clinmed.2022-0113