We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Needle‐free epicutaneous For t 2 DNA vaccine is effective for preventing and treating biting midge Forcipomyia taiwana allergy in a murine model.
- Authors
Lee, Mey‐ Fann; Wu, Chi‐Sheng; Lin, Shyh‐Jye; Chen, Yi‐Hsing
- Abstract
Needle-free epicutaneous For t 2 DNA vaccine is effective for preventing and treating biting midge Forcipomyia taiwana allergy in a murine model After epicutaneous DNA vaccination, in addition to allergen-induced itch, the changes of multiple biomarkers suggest that immune tolerance was induced after the epicutaneous DNA vaccine. It is possible that the DNA vaccine passes the epidermis via the hair follicles as the skin is tape-stripped before epicutaneous vaccination.6 The mode of this anti-allergic epicutaneous DNA vaccine may potentially be used in other specific immunotherapies for other allergens.
- Subjects
CERATOPOGONIDAE; DNA vaccines; VACCINE effectiveness; ALLERGIES; SKIN absorption; ITCHING
- Publication
Allergy, 2022, Vol 77, Issue 2, p678
- ISSN
0105-4538
- Publication type
Article
- DOI
10.1111/all.15141