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Pulmonary Fibrosis Induced by γ-Herpesvirus in Aged Mice Is Associated With Increased Fibroblast Responsiveness to Transforming Growth Factor-β.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 7, p. 714, doi. 10.1093/gerona/glr211
By:
- Naik, Payal N.;
- Horowitz, Jeffrey C.;
- Moore, Thomas A.;
- Wilke, Carol A.;
- Toews, Galen B.;
- Moore, Bethany B.
Publication type:
Article
Pulmonary fibrosis induced by γ-herpesvirus in aged mice is associated with increased fibroblast responsiveness to transforming growth factor-β.
Published in:
2012
By:
- Naik PN;
- Horowitz JC;
- Moore TA;
- Wilke CA;
- Toews GB;
- Moore BB;
- Naik, Payal N;
- Horowitz, Jeffrey C;
- Moore, Thomas A;
- Wilke, Carol A;
- Toews, Galen B;
- Moore, Bethany B
Publication type:
journal article
Fibroblast growth factors and pulmonary fibrosis: it's more complex than it sounds.
Published in:
Journal of Pathology, 2017, v. 241, n. 1, p. 6, doi. 10.1002/path.4825
By:
- Kim, Kevin K;
- Sisson, Thomas H;
- Horowitz, Jeffrey C
Publication type:
Article
Plakoglobin expression in fibroblasts and its role in idiopathic pulmonary fibrosis.
Published in:
2015
By:
- Matthes, Stephanie A.;
- LaRouere, Thomas J.;
- Horowitz, Jeffrey C.;
- White, Eric S.
Publication type:
journal article
Persistent hypoxia promotes myofibroblast differentiation via GPR‐81 and differential regulation of LDH isoenzymes in normal and idiopathic pulmonary fibrosis fibroblasts.
Published in:
Physiological Reports, 2023, v. 11, n. 17, p. 1, doi. 10.14814/phy2.15759
By:
- Nho, Richard S.;
- Rice, Cami;
- Prasad, Jayendra;
- Bone, Hannah;
- Farkas, Laszlo;
- Rojas, Mauricio;
- Horowitz, Jeffrey C.
Publication type:
Article
Phosphodiesterase 4 inhibition reduces lung fibrosis following targeted type II alveolar epithelial cell injury.
Published in:
Physiological Reports, 2018, v. 6, n. 12, p. 1, doi. 10.14814/phy2.13753
By:
- Sisson, Thomas H.;
- Christensen, Paul J.;
- Muraki, Yo;
- Dils, Anthony J.;
- Chibucos, Lauren;
- Subbotina, Natalya;
- Tohyama, Kimio;
- Horowitz, Jeffrey C.;
- Matsuo, Takanori;
- Bailie, Marc;
- Nikam, Sham;
- Hazama, Masatoshi
Publication type:
Article
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.
Published in:
Nature Medicine, 2009, v. 15, n. 9, p. 1077, doi. 10.1038/nm.2005
By:
- Hecker, Louise;
- Vittal, Ragini;
- Jones, Tamara;
- Jagirdar, Rajesh;
- Luckhardt, Tracy R.;
- Horowitz, Jeffrey C.;
- Pennathur, Subramaniam;
- Martinez, Fernando J.;
- Thannickal, Victor J.
Publication type:
Article
PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.
Published in:
Journal of Pathology, 2012, v. 228, n. 2, p. 170, doi. 10.1002/path.3992
By:
- Osterholzer, John J;
- Christensen, Paul J;
- Lama, Vibha;
- Horowitz, Jeffrey C;
- Hattori, Noboru;
- Subbotina, Natalya;
- Cunningham, Andrew;
- Lin, Yujing;
- Murdock, Benjamin J;
- Morey, Roger E;
- Olszewski, Michal A;
- Lawrence, Daniel A;
- Simon, Richard H;
- Sisson, Thomas H
Publication type:
Article
Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis.
Published in:
Scientific Reports, 2016, p. 37445, doi. 10.1038/srep37445
By:
- Chanda, Diptiman;
- Kurundkar, Ashish;
- Rangarajan, Sunad;
- Locy, Morgan;
- Bernard, Karen;
- Sharma, Nirmal S.;
- Logsdon, Naomi J.;
- Liu, Hui;
- Crossman, David K.;
- Horowitz, Jeffrey C.;
- De Langhe, Stijn;
- Thannickal, Victor J.
Publication type:
Article
Serum Ferritin as a Predictor of Outcomes in Hospitalized Patients with Covid-19 Pneumonia.
Published in:
Journal of Intensive Care Medicine, 2023, v. 38, n. 1, p. 21, doi. 10.1177/08850666221113252
By:
- Shakaroun, Dania A.;
- Lazar, Michael H.;
- Horowitz, Jeffrey C.;
- Jennings, Jeffrey H.
Publication type:
Article
SMAD-Independent Down-Regulation of Caveolin-1 by TGF-β: Effects on Proliferation and Survival of Myofibroblasts.
Published in:
PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116995
By:
- Sanders, Yan Y.;
- Cui, Zongbin;
- Le Saux, Claude Jourdan;
- Horowitz, Jeffrey C.;
- Rangarajan, Sunad;
- Kurundkar, Ashish;
- Antony, Veena B.;
- Thannickal, Victor J.
Publication type:
Article
Fibroblast Activating Protein: Skimming the Surface of Molecular Imaging to Assess Fibrotic Disease Activity.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 2, p. 122, doi. 10.1164/rccm.202208-1638ED
By:
- Montesi, Sydney B.;
- Horowitz, Jeffrey C.
Publication type:
Article
Investigating Matrix-Fibroblast Regulation of MicroRNAs. A Dice(r)y Proposition.
Published in:
2018
By:
- Horowitz, Jeffrey C
Publication type:
Editorial
Discoidin Domain Receptor 2 Signaling Regulates Fibroblast Apoptosis through PDK1/Akt.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2018, v. 59, n. 3, p. 295, doi. 10.1165/rcmb.2017-0419OC
By:
- Shijing Jia;
- Agarwal, Manisha;
- Yang, Jibing;
- Horowitz, Jeffrey C.;
- White, Eric S.;
- Kim, Kevin K.
Publication type:
Article
Releasing Tensin.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 56, n. 4, p. 417, doi. 10.1165/rcmb.2016-0417ed
By:
- Horowitz, Jeffrey C.
Publication type:
Article
Targeting Inhibitor of Apoptosis Proteins Protects from Bleomycin-Induced Lung Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2016, v. 54, n. 4, p. 482, doi. 10.1165/rcmb.2015-0148OC
By:
- Ashley, Shanna L.;
- Sisson, Thomas H.;
- Wheaton, Amanda K.;
- Kim, Kevin K.;
- Wilke, Carol A.;
- Ajayi, Iyabode O.;
- Subbotina, Natalya;
- Shaomeng Wang;
- Duckett, Colin S.;
- Moore, Bethany B.;
- Horowitz, Jeffrey C.
Publication type:
Article
Targeting inhibitor of apoptosis proteins protects from bleomycin-induced lung fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2016, v. 54, n. 4, p. E1, doi. 10.1165/rcmb.2015-0148oc
By:
- Ashley, Shanna L.;
- Sisson, Thomas H.;
- Wheaton, Amanda K.;
- Kim, Kevin K.;
- Wilke, Carol A.;
- Ajayi, Iyabode O.;
- Subbotina, Natalya;
- Shaomeng Wang;
- Duckett, Colin S.;
- Moore, Bethany B.;
- Horowitz, Jeffrey C.
Publication type:
Article
X-Linked Inhibitor of Apoptosis Regulates Lung Fibroblast Resistance to Fas-Mediated Apoptosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 1, p. 86, doi. 10.1165/rcmb.2012-0224OC
By:
- Ajayi, Iyabode O.;
- Sisson, Thomas H.;
- Higgins, Peter D. R.;
- Booth, Adam J.;
- Sagana, Rommel L.;
- Huang, Steven K.;
- White, Eric S.;
- King, Jessie E.;
- Moore, Bethany B.;
- Horowitz, Jeffrey C.
Publication type:
Article
Endothelin-1 and Transforming Growth Factor-β1 Independently Induce Fibroblast Resistance to Apoptosis via AKT Activation.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2009, v. 41, n. 4, p. 484, doi. 10.1165/rcmb.2008-0447OC
By:
- Kulasekaran, Priya;
- Scavone, Casey A.;
- Rogers, David S.;
- Arenberg, Douglas A.;
- Thannickal, Victor J.;
- Horowitz, Jeffrey C.
Publication type:
Article
Plasminogen Activation--Induced Pericellular Fibronectin Proteolysis Promotes Fibroblast Apoptosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2008, v. 38, n. 1, p. 78, doi. 10.1165/rcmb.2007-0174OC
By:
- Horowitz, Jeffrey C.;
- Rogers, David S.;
- Simon, Richard H.;
- Sisson, Thomas H.;
- Thannickal, Victor J.
Publication type:
Article
Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli.
Published in:
2018
By:
- Dodi, Amos E.;
- Ajayi, Iyabode O.;
- Chang, Christine;
- Beard, Meghan;
- Ashley, Shanna L.;
- Huang, Steven K.;
- Thannickal, Victor J.;
- Tschumperlin, Daniel J.;
- Sisson, Thomas H.;
- Horowitz, Jeffrey C.
Publication type:
journal article
Increased COVID-19 Mortality and Deficient SARS-CoV-2 Immune Response Are Not Associated with Higher Levels of Endemic Coronavirus Antibodies.
Published in:
Immuno, 2023, v. 3, n. 3, p. 330, doi. 10.3390/immuno3030020
By:
- Adhikari, Bindu;
- Oltz, Eugene M.;
- Bednash, Joseph S.;
- Horowitz, Jeffrey C.;
- Amimo, Joshua O.;
- Raev, Sergei A.;
- Fernández, Soledad;
- Anghelina, Mirela;
- Liu, Shan-Lu;
- Rubinstein, Mark P.;
- Jones, Daniel M.;
- Saif, Linda J.;
- Vlasova, Anastasia N.
Publication type:
Article
Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1325243
By:
- Adhikari, Bindu;
- Bednash, Joseph S.;
- Horowitz, Jeffrey C.;
- Rubinstein, Mark P.;
- Vlasova, Anastasia N.
Publication type:
Article
Prostaglandin E<sub>2</sub> induces fibroblast apoptosis by modulating multiple survival pathways.
Published in:
FASEB Journal, 2009, v. 23, n. 12, p. 4317, doi. 10.1096/fj.08-128801
By:
- Huang, Steven K.;
- White, Eric S.;
- Wettlaufer, Scott H.;
- Grifka, Heather;
- Hogaboam, Cory M.;
- Thannickal, Victor J.;
- Horowitz, Jeffrey C.;
- Peters-Golden, Marc
Publication type:
Article
Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts.
Published in:
FASEB Journal, 2005, v. 19, n. 7, p. 854, doi. 10.1096/fj.04-2882fje
By:
- Waghray, Meghna;
- Zongbin Cui;
- Horowitz, Jeffrey C.;
- Subramanian, Indhu M.;
- Martinez, Fernando J.;
- Toews, Galen B.;
- Thannickal, Victor J.
Publication type:
Article
Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2012, v. 186, n. 9, p. 866, doi. 10.1164/rccm.201204-0754oc
By:
- Booth, Adam J.;
- Hadley, Ryan;
- Cornett, Ashley M.;
- Dreffs, Alyssa A.;
- Matthes, Stephanie A.;
- Tsui, Jessica L.;
- Weiss, Kevin;
- Horowitz, Jeffrey C.;
- Fiore, Vincent F.;
- Barker, Thomas H.;
- Moore, Bethany B.;
- Martinez, Fernando J.;
- Niklason, Laura E.;
- White, Eric S.
Publication type:
Article
Prostaglandin E2's new trick: "decider" of differential alveolar cell life and death.
Published in:
2010
By:
- Horowitz JC;
- Peters-Golden M;
- Horowitz, Jeffrey C;
- Peters-Golden, Marc
Publication type:
commentary
Stress in the ER (endoplasmic reticulum): a matter of life and death for epithelial cells.
Published in:
2008
By:
- Horowitz JC;
- Limper AH;
- Horowitz, Jeffrey C;
- Limper, Andrew H
Publication type:
commentary
Eosinophilic reactive airways disease after immune checkpoint inhibitor treatment.
Published in:
2024
By:
- Cordial, Parker;
- Bentley, Ian D.;
- Horowitz, Jeffrey C.;
- Ho, Kevin
Publication type:
Case Study
Pathogenesis of pneumonia and acute lung injury.
Published in:
Clinical Science, 2022, v. 136, n. 10, p. 747, doi. 10.1042/CS20210879
By:
- Long, Matthew E.;
- Mallampalli, Rama K.;
- Horowitz, Jeffrey C.
Publication type:
Article
Longitudinal transcriptomic analysis reveals persistent enrichment of iron homeostasis and erythrocyte function pathways in severe COVID-19 ARDS.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1397629
By:
- Eltobgy, Moemen;
- Johns, Finny;
- Farkas, Daniela;
- Leuenberger, Laura;
- Cohen, Sarah P.;
- Ho, Kevin;
- Karow, Sarah;
- Swoope, Gabrielle;
- Pannu, Sonal;
- Horowitz, Jeffrey C.;
- Mallampalli, Rama K.;
- Englert, Joshua A.;
- Bednash, Joseph S.
Publication type:
Article
Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1325243
By:
- Adhikari, Bindu;
- Bednash, Joseph S.;
- Horowitz, Jeffrey C.;
- Rubinstein, Mark P.;
- Vlasova, Anastasia N.
Publication type:
Article

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