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- Title
Combination of lateral ventricular puncture and catheterization with different doses of urokinase in the treatment of ventricular hemorrhage under CT multimodal imaging.
- Authors
Zhifu Song; Yulan Gan; Xueping Huang; Xiaolin Huang; Gonghong Liu; Bing Kong; Wenyou Wu
- Abstract
Purpose: To study the clinical effectiveness of lateral ventricular puncture and catheterization in combination with urokinase in the treatment of intraventricular hemorrhage (IVH) under computed tomography (CT) multimodal imaging. Methods: Eighty-four IVH patients were selected and assigned to high- and low-dose urokinase groups. The clinical efficacy of the combination of lateral ventricle puncture and drainage at different doses of urokinase under CT multimodal imaging in the treatment of IVH, was determined. Results: Compared with the low-dose urokinase group, postoperative waking time, postoperative extubation time and discharge time in the high-dose group were markedly better in high-dose urokinase group, while GCS score after treatment was lower in the high-dose group, with higher total effectiveness in the high-dose urokinase group. There was a significantly higher hematoma clearance in the highdose group on the 3rd day of treatment (p < 0.001), while the total incidence of postoperative complications were markedly lower in the high-dose group (p < 0.05). Conclusion: The combination of lateral ventricular puncture and drainage with high-dose urokinase under CT multimodal imaging enhances the recovery of consciousness in IVH patients. Therefore, the combined treatment has great potentials for clinical application.
- Subjects
COMPUTED tomography; UROKINASE; CATHETERIZATION; INTRAVENTRICULAR hemorrhage; HEMORRHAGE; IMAGE reconstruction algorithms; FLUOROSCOPY
- Publication
Tropical Journal of Pharmaceutical Research, 2021, Vol 20, Issue 12, p2645
- ISSN
1596-5996
- Publication type
Article
- DOI
10.4314/tjpr.v20i12.27