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- Title
Type B insulin resistance syndrome with Scleroderma successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection: a case report.
- Authors
Guo-Qing Yang; Yi-Jun Li; Jing-Tao Dou; Bao-An Wang; Ju-Ming Lu; Yi-Ming Mu
- Abstract
Background: Type B insulin resistance is a rare autoimmune disease characterized by the presence of autoantibodies against the insulin receptor. Helicobacter pylori (H pylori) infection may play a causative role in the autoimmune diseases. Case presentation: Here, we present a rare case of a 48-year old female patient, who had type B insulin resistance with systemic scleroderma and was successfully treated with multiple immune suppressants after eradication of Helicobacter pylori infection. Conclusion: The present case suggests H pylori infection-related pathological mechanism may contribute to type B insulin resistance syndrome and autoimmune disorders. Treatment toward H pylori may be helpful to relieve syndrome of type B insulin resistance for H pylori positive patients.
- Subjects
SYSTEMIC scleroderma; IMMUNOSUPPRESSIVE agents; CONTENT analysis; HELICOBACTER diseases; HISTOLOGY; INSULIN resistance; RESEARCH funding; WESTERN immunoblotting; DATA analysis software; DISEASE eradication; DIAGNOSIS
- Publication
BMC Endocrine Disorders, 2016, Vol 16, p1
- ISSN
1472-6823
- Publication type
Article
- DOI
10.1186/s12902-016-0099-5