OpenURL Connection Search

Select item for more details and to access through your institution.

Safety and Tolerability of the Chymase Inhibitor Fulacimstat in Patients With Left Ventricular Dysfunction After Myocardial Infarction—Results of the CHIARA MIA 1 Trial.
Published in:
Clinical Pharmacology in Drug Development, 2019, v. 8, n. 7, p. 942, doi. 10.1002/cpdd.633
By:
- Düngen, Hans‐Dirk;
- Kober, Lars;
- Nodari, Savina;
- Schou, Morten;
- Otto, Christiane;
- Becka, Michael;
- Kanefendt, Friederike;
- Winkelmann, Bernhard R.;
- Gislason, Gunnar;
- Richard, Frank;
- Nielsen, Olav Wendelboe;
- Gheorghiade, Mihai;
- Senni, Michele
Publication type:
Article
Effects of Tolvaptan, a Vasopressin Antagonist, in Patients Hospitalized With Worsening Heart Failure: A Randomized Controlled Trial.
Published in:
JAMA: Journal of the American Medical Association, 2004, v. 291, n. 16, p. 1963, doi. 10.1001/jama.291.16.1963
By:
- Gheorghiade, Mihai;
- Gattis, Wendy A.;
- O'Connor, Christopher M.;
- Adams, Jr, Kirkwood F.;
- Elkayam, Uri;
- Barbagelata, Alejandro;
- Ghali, Jalal K.;
- Benza, Raymond L.;
- McGrew, Frank A.;
- Klapholz, Marc;
- Ouyang, John;
- Orlandi, Cesare
Publication type:
Article
Short-term Intravenous Milrinone for Acute Exacerbation of Chronic Heart Failure: A Randomized Controlled Trial.
Published in:
JAMA: Journal of the American Medical Association, 2002, v. 287, n. 12, p. 1541, doi. 10.1001/jama.287.12.1541
By:
- Cuffe, Michael S.;
- Califf, Robert M.;
- Adams, Jr, Kirkwood F.;
- Benza, Raymond;
- Bourge, Robert;
- Colucci, Wilson S.;
- Massie, Barry M.;
- O'Connor, Christopher M.;
- Pina, Ileana;
- Quigg, Rebecca;
- Silver, Marc A.;
- Gheorghiade, Mihai
Publication type:
Article
Assessment of Dyspnea Early in Acute Heart Failure: Patient Characteristics and Response Differences Between Likert and Visual Analog Scales Valoración Precoz de la Disnea en la Insuficiencia Cardiaca Aguda: Characterísticas del...
Published in:
2014
By:
- Pang, Peter S.;
- Collins, Sean P.;
- Sauser, Kori;
- Andrei, Adin-Cristian;
- Storrow, Alan B.;
- Hollander, Judd E.;
- Tavares, Miguel;
- Spinar, Jindrich;
- Macarie, Cezar;
- Raev, Dimitar;
- Nowak, Richard;
- Gheorghiade, Mihai;
- Mebazaa, Alexandre
Publication type:
Journal Article
Assessment of Dyspnea Early in Acute Heart Failure: Patient Characteristics and Response Differences Between Likert and Visual Analog Scales Valoración Precoz de la Disnea en la Insuficiencia Cardiaca Aguda: Characterísticas del Paciente y Diferencias de Respuesta entre las Escalas Likert y las Escalas Visuales Analógicas
Published in:
Academic Emergency Medicine, 2014, v. 21, n. 6, p. 659, doi. 10.1111/acem.12390
By:
- Pang, Peter S.;
- Collins, Sean P.;
- Sauser, Kori;
- Andrei, Adin‐Cristian;
- Storrow, Alan B.;
- Hollander, Judd E.;
- Tavares, Miguel;
- Spinar, Jindrich;
- Macarie, Cezar;
- Raev, Dimitar;
- Nowak, Richard;
- Gheorghiade, Mihai;
- Mebazaa, Alexandre;
- Hiestand, Brian
Publication type:
Article
Calcium Antagonists in Clinical Medicine (Book).
Published in:
1993
By:
- Gheorghiade, Mihai
Publication type:
Book Review
Pharmacist interventions to improve the management of coronary artery disease.
Published in:
American Journal of Health-System Pharmacy, 2004, v. 61, n. 24, p. 2672, doi. 10.1093/ajhp/61.24.2672
By:
- Chapman, Noelle R. M.;
- Fotis, Michael A.;
- Yarnold, Paul R.;
- Gheorghiade, Mihai
Publication type:
Article
Biomarkers in Acute Heart Failure Syndromes - Are They Fulfilling Their Promise?
Published in:
Cardiology, 2011, v. 120, n. 1, p. 19, doi. 10.1159/000332586
By:
- Shah, Ami N.;
- Nodari, Savina;
- Gheorghiade, Mihai
Publication type:
Article
Acute Heart Failure Clinical Drug Development: From Planning to Proof of Activity to Phase III.
Published in:
Cardiology, 2010, v. 116, n. 4, p. 292, doi. 10.1159/000318048
By:
- Cotter, Gad;
- Voors, Adriaan A.;
- Weatherley, Beth Davison;
- Pang, Peter S.;
- Teerlink, John R.;
- Filippatos, Gerasimos;
- Ponikowski, Piotr;
- Milo-Cotter, Olga;
- Dittrich, Howard;
- Teichman, Sam L.;
- Adams, Kirkwood F.;
- Gheorghiade, Mihai;
- Metra, Marco
Publication type:
Article
Mineralocorticoid receptor antagonism: therapeutic potential in acute heart failure syndromes.
Published in:
European Heart Journal, 2011, v. 32, n. 21, p. 2626, doi. 10.1093/eurheartj/ehr170
By:
- Albaghdadi, Mazen;
- Gheorghiade, Mihai;
- Pitt, Bertram
Publication type:
Article
Changes in renal function during hospitalization and soon after discharge in patients admitted for worsening heart failure in the placebo group of the EVEREST trial.
Published in:
European Heart Journal, 2011, v. 32, n. 20, p. 2563
By:
- Blair, John E.A.;
- Pang, Peter S.;
- Schrier, Robert W.;
- Metra, Marco;
- Traver, Brian;
- Cook, Thomas;
- Campia, Umberto;
- Ambrosy, Andrew;
- Burnett, John C.;
- Grinfeld, Liliana;
- Maggioni, Aldo P.;
- Swedberg, Karl;
- Udelson, James E.;
- Zannad, Faiez;
- Konstam, Marvin A.;
- Gheorghiade, Mihai
Publication type:
Article
Beyond dyspnoea as an endpoint in acute heart failure trials.
Published in:
European Heart Journal, 2011, v. 32, n. 12, p. 1442, doi. 10.1093/eurheartj/ehr044
By:
- Gheorghiade, Mihai;
- Ruschitzka, Frank
Publication type:
Article
The impact of early standard therapy on dyspnoea in patients with acute heart failure: the URGENT-dyspnoea study.
Published in:
European Heart Journal, 2010, v. 31, n. 7, p. 832, doi. 10.1093/eurheartj/ehp458
By:
- Mebazaa, Alexandre;
- Pang, Peter S.;
- Tavares, Miguel;
- Collins, Sean P.;
- Storrow, Alan B.;
- Laribi, Said;
- Andre, Stephanie;
- Mark Courtney, Daniel;
- Hasa, Jennifer;
- Spinar, Jindrich;
- Masip, Josep;
- Frank Peacock, William;
- Sliwa, Karen;
- Gayat, Etienne;
- Filippatos, Gerasimos;
- Cleland, John G.F.;
- Gheorghiade, Mihai
Publication type:
Article
The current and future management of acute heart failure syndromes.
Published in:
European Heart Journal, 2010, v. 31, n. 7, p. 784, doi. 10.1093/eurheartj/ehq040
By:
- Pang, Peter S.;
- Komajda, Michel;
- Gheorghiade, Mihai
Publication type:
Article
Effects of tolvaptan on dyspnoea relief from the EVEREST trials.
Published in:
European Heart Journal, 2009, v. 30, n. 18, p. 2233
By:
- Pang, Peter S.;
- Konstam, Marvin A.;
- Krasa, Holly B.;
- Swedberg, Karl;
- Zannad, Faiez;
- Blair, John E.A.;
- Zimmer, Christopher;
- Teerlink, John R.;
- Maggioni, Aldo P.;
- Burnett, John C.;
- Grinfeld, Liliana;
- Ouyang, John;
- Udelson, James E.;
- Gheorghiade, Mihai
Publication type:
Article
Evidence-based use of levosimendan in different clinical settings.
Published in:
European Heart Journal, 2006, v. 27, n. 16, p. 1908, doi. 10.1093/eurheartj/ehi875
By:
- De Luca, Leonardo;
- Colucci, Wilson S.;
- Nieminen, Markku S.;
- Massie, Barry M.;
- Gheorghiade, Mihai
Publication type:
Article
Digoxin and reduction in mortality and hospitalization in systolic and diastolic heart failure at low serum digoxin concentrations: reply.
Published in:
European Heart Journal, 2006, v. 27, n. 13, p. 1630, doi. 10.1093/eurheartj/ehl046
By:
- Ahmed, Ali;
- Rich, Michael W.;
- Aban, Inmaculada B.;
- Gheorghiade, Mihai
Publication type:
Article
Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods.
Published in:
European Heart Journal, 2006, v. 27, n. 12, p. 1431, doi. 10.1093/eurheartj/ehi890
By:
- Ahmed, Ali;
- Husain, Ahsan;
- Love, Thomas E.;
- Gambassi, Giovanni;
- Dell'Italia, Louis J.;
- Francis, Gary S.;
- Gheorghiade, Mihai;
- Allman, Richard M.;
- Meleth, Sreelatha;
- Bourge, Robert C.
Publication type:
Article
Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial.
Published in:
European Heart Journal, 2006, v. 27, n. 2, p. 178, doi. 10.1093/eurheartj/ehi687
By:
- Ahmed, Ali;
- Rich, Michael W.;
- Love, Thomas E.;
- Lloyd-Jones, Donald M.;
- Aban, Inmaculada B.;
- Colucci, Wilson S.;
- Adams, Kirkwood F.;
- Gheorghiade, Mihai
Publication type:
Article
Reconsidering the Role for Digoxin in the Management of Acute Heart Failure Syndromes.
Published in:
2009
By:
- Gheorghiade, Mihai;
- Braunwald, Eugene
Publication type:
Opinion
QRS Duration in Patients Hospitalized for Worsening Heart Failure.
Published in:
2008
By:
- Gheorghiade, Mihai;
- Wang, Norman C.;
- Cook, Thomas
Publication type:
Letter
Heart failure with preserved ejection fraction: treat now by treating comorbidities.
Published in:
2008
By:
- Shah SJ;
- Gheorghiade M;
- Shah, Sanjiv J;
- Gheorghiade, Mihai
Publication type:
journal article
Heart Failure With Preserved Ejection Fraction.
Published in:
2008
By:
- Shah, Sanjiv J.;
- Gheorghiade, Mihai
Publication type:
Editorial
Clinical Implications of QRS Duration in Patients Hospitalized With Worsening Heart Failure and Reduced Left Ventricular Ejection Fraction.
Published in:
JAMA: Journal of the American Medical Association, 2008, v. 299, n. 22, p. 2656, doi. 10.1001/jama.299.22.2656
By:
- Wang, Norman C.;
- Maggioni, Aldo P.;
- Konstam, Marvin A.;
- Zannad, Faiez;
- Krasa, Holly B.;
- Burnett Jr., John C.;
- Grinfeld, Liliana;
- Swedberg, Karl;
- Udelson, James E.;
- Cook, Thomas;
- Traver, Brain;
- Zimmer, Christopher;
- Orlandi, Cesare;
- Gheorghiade, Mihai
Publication type:
Article
Short-term clinical effects of tolvaptan, an oral vasopressin antagonist, in patients hospitalized for heart failure: the EVEREST Clinical Status Trials.
Published in:
2007
By:
- Gheorghiade M;
- Konstam MA;
- Burnett JC Jr.;
- Grinfeld L;
- Maggioni AP;
- Swedberg K;
- Udelson JE;
- Zannad F;
- Cook T;
- Ouyang J;
- Zimmer C;
- Orlandi C;
- Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan Investigators;
- Gheorghiade, Mihai;
- Konstam, Marvin A;
- Burnett, John C Jr;
- Grinfeld, Liliana;
- Maggioni, Aldo P;
- Swedberg, Karl;
- Udelson, James E
Publication type:
journal article
Effects of oral tolvaptan in patients hospitalized for worsening heart failure: the EVEREST Outcome Trial.
Published in:
2007
By:
- Konstam MA;
- Gheorghiade M;
- Burnett JC Jr.;
- Grinfeld L;
- Maggioni AP;
- Swedberg K;
- Udelson JE;
- Zannad F;
- Cook T;
- Ouyang J;
- Zimmer C;
- Orlandi C;
- Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan Investigators;
- Konstam, Marvin A;
- Gheorghiade, Mihai;
- Burnett, John C Jr;
- Grinfeld, Liliana;
- Maggioni, Aldo P;
- Swedberg, Karl;
- Udelson, James E
Publication type:
journal article
Effects of Oral Tolvaptan in Patients Hospitalized for Worsening Heart Failure.
Published in:
JAMA: Journal of the American Medical Association, 2007, v. 297, n. 12, p. 1319, doi. 10.1001/jama.297.12.1319
By:
- Konstam, Marvin A.;
- Gheorghiade, Mihai;
- Burnett, Jr., John C.;
- Grinfeld, Liliana;
- Maggioni, Aldo P.;
- Swedberg, Karl;
- Udelson, James E.;
- Zannad, Faiez;
- Cook, Thomas;
- Ouyang, John;
- Zimmer, Christopher;
- Orlandi, Cesare
Publication type:
Article
Short-term Clinical Effects of Tolvaptan, an Oral Vasopressin Antagonist, in Patients Hospitalized for Heart Failure.
Published in:
JAMA: Journal of the American Medical Association, 2007, v. 297, n. 12, p. 1332, doi. 10.1001/jama.297.12.1332
By:
- Gheorghiade, Mihai;
- Konstam, Marvin A.;
- Bennett Jr., John C.;
- Grinfeld, Liliana;
- Maggioni, Aldo P.;
- Swedberg, Karl;
- Udelson, James E.;
- Zannad, Faiez;
- Cook, Thomas;
- Ouyang, John;
- Zimmer, Christopher;
- Orlandi, Cesare
Publication type:
Article
Systolic Blood Pressure and Outcomes in Patients Hospitalized With Acute Heart Failure.
Published in:
2007
By:
- Gheorghiade, Mihai;
- Fonarow, Gregg C.
Publication type:
Letter
Association Between Performance Measures and Clinical Outcomes for Patients Hospitalized With Heart Failure.
Published in:
JAMA: Journal of the American Medical Association, 2007, v. 297, n. 1, p. 61, doi. 10.1001/jama.297.1.61
By:
- Fonarow, Gregg C.;
- Abraham, William T.;
- Albert, Nancy M.;
- Stough, Wendy Gattis;
- Gheorghiade, Mihai;
- Greenberg, Barry H.;
- O'Connor, Christopher M.;
- Pieper, Karen;
- Sun, Jie Lena;
- Yancy, Clyde;
- Young, James B.
Publication type:
Article
Systolic Blood Pressure at Admission, Clinical Characteristics, and Outcomes in Patients Hospitalized With Acute Heart Failure.
Published in:
JAMA: Journal of the American Medical Association, 2006, v. 296, n. 18, p. 2217, doi. 10.1001/jama.296.18.2217
By:
- Gheorghiade, Mihai;
- Abraham, Wiliam T.;
- Albert, Nancy M.;
- Greenberg, Barry H.;
- O'Connor, Christopher M.;
- She, Lilin;
- Stough, Wendy Gattis;
- Yancy, Clyce W.;
- Young, James B.;
- Fonarow, Gregg C.
Publication type:
Article
Factors Associated with Improvement in Utilization of Cardiac Resynchronization Therapy in Eligible Heart Failure Patients: Findings from IMPROVE HF.
Published in:
Pacing & Clinical Electrophysiology, 2013, v. 36, n. 4, p. 433, doi. 10.1111/pace.12090
By:
- SHUKLA, ASHISH;
- CURTIS, ANNE B.;
- MEHRA, MANDEEP R.;
- ALBERT, NANCY M.;
- GHEORGHIADE, MIHAI;
- HEYWOOD, J. THOMAS;
- LIU, YANG;
- O'CONNOR, CHRISTOPHER M.;
- REYNOLDS, DWIGHT;
- WALSH, MARY NORINE;
- YANCY, CLYDE W.;
- FONAROW, GREGG C.
Publication type:
Article
Factors Associated with Improvement in Guideline-Based Use of ICDs in Eligible Heart Failure Patients.
Published in:
Pacing & Clinical Electrophysiology, 2012, v. 35, n. 2, p. 135, doi. 10.1111/j.1540-8159.2011.03279.x
By:
- MEHRA, MANDEEP R.;
- ALBERT, NANCY M.;
- CURTIS, ANNE B.;
- GHEORGHIADE, MIHAI;
- HEYWOOD, J. THOMAS;
- LIU, YANG;
- O'CONNOR, CHRISTOPHER M.;
- REYNOLDS, DWIGHT;
- WALSH, MARY NORINE;
- YANCY, CLYDE W.;
- FONAROW, GREGG C.
Publication type:
Article
Therapy for acute heart failure syndromes.
Published in:
Current Cardiology Reports, 2009, v. 11, n. 3, p. 192, doi. 10.1007/s11886-009-0028-6
By:
- Donlan, Sarah;
- Quattromani, Erin;
- Pang, Peter;
- Gheorghiade, Mihai
Publication type:
Article
Mitral regurgitation in chronic heart failure: More questions than answers?
Published in:
Current Cardiology Reports, 2004, v. 6, n. 2, p. 96, doi. 10.1007/s11886-004-0005-z
By:
- Mehra, Mandeep;
- Gheorghiade, Mihai;
- Bonow, Robert
Publication type:
Article
Medication dosing for heart failure with reduced ejection fraction - opportunities and challenges.
Published in:
2019
By:
- Marti, Catherine N.;
- Fonarow, Gregg C.;
- Anker, Stefan D.;
- Yancy, Clyde;
- Vaduganathan, Muthiah;
- Greene, Stephen J.;
- Ahmed, Ali;
- Januzzi, James L.;
- Gheorghiade, Mihai;
- Filippatos, Gerasimos;
- Butler, Javed
Publication type:
journal article
Rationale and design of the phase 2b clinical trials to study the effects of the partial adenosine A1-receptor agonist neladenoson bialanate in patients with chronic heart failure with reduced (PANTHEON) and preserved (PANACHE) ejection fraction.
Published in:
2018
By:
- Voors, Adriaan A.;
- Shah, Sanjiv J.;
- Bax, Jeroen J.;
- Butler, Javed;
- Gheorghiade, Mihai;
- Hernandez, Adrian F.;
- Kitzman, Dalane W.;
- McMurray, John J.V.;
- Wirtz, Antonieta Bomfim;
- Lanius, Vivian;
- van der Laan, Michael;
- Solomon, Scott D.
Publication type:
journal article
Past, present, and future of acute heart failure clinical trials-a high-risk population in search of a strategy.
Published in:
2018
By:
- Butler, Javed;
- Stockbridge, Norman;
- Gheorghiade, Mihai
Publication type:
journal article
Lessons learned in acute heart failure.
Published in:
2018
By:
- Cheema, Baljash;
- Ambrosy, Andrew P.;
- Kaplan, Rachel M.;
- Senni, Michele;
- Fonarow, Gregg C.;
- Chioncel, Ovidiu;
- Butler, Javed;
- Gheorghiade, Mihai
Publication type:
journal article
Plasma renin activity, response to aliskiren, and clinical outcomes in patients hospitalized for heart failure: the ASTRONAUT trial.
Published in:
2018
By:
- Vaduganathan, Muthiah;
- Cheema, Baljash;
- Cleveland, Erin;
- Sankar, Kamya;
- Subacius, Haris;
- Fonarow, Gregg C.;
- Solomon, Scott D.;
- Lewis, Eldrin F.;
- Greene, Stephen J.;
- Maggioni, Aldo P.;
- Böhm, Michael;
- Zannad, Faiez;
- Butler, Javed;
- Gheorghiade, Mihai
Publication type:
journal article
Pre-discharge and early post-discharge troponin elevation among patients hospitalized for heart failure with reduced ejection fraction: findings from the ASTRONAUT trial.
Published in:
2018
By:
- Greene, Stephen J.;
- Butler, Javed;
- Fonarow, Gregg C.;
- Subacius, Haris P.;
- Ambrosy, Andrew P.;
- Vaduganathan, Muthiah;
- Triggiani, Marco;
- Solomon, Scott D.;
- Lewis, Eldrin F.;
- Maggioni, Aldo P.;
- Böhm, Michael;
- Chioncel, Ovidiu;
- Nodari, Savina;
- Senni, Michele;
- Zannad, Faiez;
- Gheorghiade, Mihai;
- for the ASTRONAUT Investigators and Coordinators;
- ASTRONAUT Investigators and Coordinators
Publication type:
journal article
Real-world dosing of evidence-based medications for heart failure: embracing guideline recommendations and clinical judgement.
Published in:
2017
By:
- Ambrosy, Andrew P.;
- Gheorghiade, Mihai
Publication type:
Editorial
Clinical trials in acute heart failure: beginning of the end or end of the beginning?
Published in:
2017
By:
- Ambrosy, Andrew P.;
- Butler, Javed;
- Gheorghiade, Mihai
Publication type:
Editorial
Protein turnover in the failing heart: an ever-changing landscape.
Published in:
2017
By:
- Cheema, Baljash S.;
- Sabbah, Hani N.;
- Greene, Stephen J.;
- Gheorghiade, Mihai
Publication type:
Editorial
Clinical profiles in acute heart failure: one size fits all or not at all?
Published in:
2017
By:
- Ambrosy, Andrew P.;
- Gheorghiade, Mihai
Publication type:
Editorial
Finding the road to recovery: therapeutic and clinical trial implications of dysfunctional viable myocardium in heart failure with reduced ejection fraction.
Published in:
European Journal of Heart Failure, 2017, v. 19, n. 7, p. 870, doi. 10.1002/ejhf.842
By:
- Greene, Stephen J.;
- Vaduganathan, Muthiah;
- Gheorghiade, Mihai
Publication type:
Article
Patient-reported outcomes in the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED ejection fraction ( SOCRATES-PRESERVED) study.
Published in:
European Journal of Heart Failure, 2017, v. 19, n. 6, p. 782, doi. 10.1002/ejhf.800
By:
- Filippatos, Gerasimos;
- Maggioni, Aldo P.;
- Lam, Carolyn S.P.;
- Pieske-Kraigher, Elisabeth;
- Butler, Javed;
- Spertus, John;
- Ponikowski, Piotr;
- Shah, Sanjiv J.;
- Solomon, Scott D.;
- Scalise, Andrea-Viviana;
- Mueller, Katharina;
- Roessig, Lothar;
- Bamber, Luke;
- Gheorghiade, Mihai;
- Pieske, Burkert
Publication type:
Article
Finding the road to recovery: therapeutic and clinical trial implications of dysfunctional viable myocardium in heart failure with reduced ejection fraction.
Published in:
2017
By:
- Greene, Stephen J;
- Vaduganathan, Muthiah;
- Gheorghiade, Mihai
Publication type:
Editorial
Influence of atrial fibrillation on post-discharge natriuretic peptide trajectory and clinical outcomes among patients hospitalized for heart failure: insights from the ASTRONAUT trial.
Published in:
2017
By:
- Greene, Stephen J.;
- Fonarow, Gregg C.;
- Solomon, Scott D.;
- Subacius, Haris P.;
- Ambrosy, Andrew P.;
- Vaduganathan, Muthiah;
- Maggioni, Aldo P.;
- Böhm, Michael;
- Lewis, Eldrin F.;
- Zannad, Faiez;
- Butler, Javed;
- Gheorghiade, Mihai;
- Böhm, Michael;
- ASTRONAUT Investigators and Coordinators
Publication type:
journal article
Targeting the vulnerable phase of heart failure: initiate novel therapies in stable patients prior to hospitalization.
Published in:
2016
By:
- Vaduganathan, Muthiah;
- Patel, Ravi B.;
- Greene, Stephen J.;
- Gheorghiade, Mihai
Publication type:
Editorial

Found: 196