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- Title
Subcutaneous changes in dermatomyositis.
- Authors
Fusade, T.; Belanyi, P.; Joly, P.; Thomine, E.; Mihout, M.E.; Lauret, PH.
- Abstract
We report the case of a 42-year-old woman with concomitant panniculitis and dermatomyositis. Painful, indurated lesions on the buttocks. thighs. arms. abdomen and breasts were associated with proximal muscle weakness. Skin biopsy revealed lobular panniculitis. arid vacuolar degeneration of epidermal basal cells. Direct immunofluorescence was negative. Serum muscle enzyme (creatine-phosphokinase) levels were elevated, arid electromyography demonstrated a myositic process. Muscle biopsy showed an intlammatory myositis. These results were consistent with dermatomyositis associated with panniculitis. Only five cases of this association have been reported previously. The relationship between these two conditions is discussed.
- Subjects
DERMATOMYOSITIS; CUTANEOUS manifestations of general diseases; MYOSITIS; BIOPSY; DIAGNOSTIC specimens; IMMUNOCYTOCHEMISTRY
- Publication
British Journal of Dermatology, 1993, Vol 128, Issue 4, p451
- ISSN
0007-0963
- Publication type
Article
- DOI
10.1111/j.1365-2133.1993.tb00209.x