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- Title
Decline of Tuberculosis Burden in Vietnam Measured by Consecutive National Surveys, 2007-2017.
- Authors
Nguyen, Hai Viet; Nguyen, Hoa Binh; Nguyen, Nhung Viet; Cobelens, Frank; Finlay, Alyssa; Dao, Cu Huy; Mirtskhulava, Veriko; Glaziou, Philippe; Pham, Huyen T. T.; de Haas, Petra; Tiemersma, Edine
- Abstract
Vietnam, a high tuberculosis (TB) burden country, conducted national TB prevalence surveys in 2007 and 2017. In both surveys participants were screened by using a questionnaire and chest radiograph; sputum samples were then collected to test for Mycobacterium tuberculosis by smear microscopy and Löwenstein-Jensen culture. Culture-positive, smear-positive, and smear-negative TB cases were defined by laboratory results, and the prevalence of tuberculosis was compared between the 2 surveys. The results showed prevalence of culture-positive TB decreased by 37% (95% CI 11.5%-55.4%), from 199 (95% CI 160-248) cases/100,000 adults in 2007 to 125 (95% CI 98-159) cases/100,000 adults in 2017. Prevalence of smear-positive TB dropped by 53% (95% CI 27.0%-69.7%), from 99 (95% CI 78-125) cases/100,000 adults to 46 (95% CI 32-68) cases/100,000 adults; smear-negative TB showed no substantial decrease. Replacing microscopy with molecular methods for primary diagnostics might enhance diagnosis of pulmonary TB cases and further lower TB burden.
- Subjects
VIETNAM; MYCOBACTERIUM tuberculosis; TUBERCULOSIS; CHEST X rays; RESPIRATORY infections; DIAGNOSIS; RESEARCH; SPUTUM; RESEARCH methodology; MEDICAL cooperation; EVALUATION research; COMPARATIVE studies; ROUTINE diagnostic tests
- Publication
Emerging Infectious Diseases, 2021, Vol 27, Issue 3, p872
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/2703.204253