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- Title
Molecular Analysis of Plasmodium ovale Variants.
- Authors
Win, Thin Thida; Jalloh, Amadu; Tantular, Indah Setyawati; Tsuboi, Takafumi; Ferreira, Marcelo Urbano; Kimura, Masatsugu; Kawamoto, Fumihiko
- Abstract
Complete DNA sequences of the small subunit ribosomal RNA (SSUrRNA) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type Plasmodium ovale isolates from Southeast Asia and compared with GenBank-available data. Three different SSUrRNA sequences (Pov 1-3) were found in each variant-type isolate, and two different SSUrRNA sequences (Poc 1-2) in each classic-type isolate. Pov 1-3 were closer to sequences previously found in the Cameroon and MAL/MAI isolates, whereas Poc 1-2 were closer to sequences previously found in two clones of the Nigerian I/CDC strain. The 3' half of Pov 1-3 was identical to the partial sequence of the SSUrRNA gene from the London School (LS) strain. Results support grouping P. ovale into two groups, the classic type (including the Nigerian I/CDC strain) and the variant type (Cameroon, MAL/MAI, and LS isolates).
- Subjects
NUCLEOTIDE sequence; DNA; RNA; GENES; PLASMODIUM
- Publication
Emerging Infectious Diseases, 2004, Vol 10, Issue 7, p1235
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid1007.030411