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- Title
Traditional Chinese Herbal Medicine Penthorum chinense Pursh: A Phytochemical and Pharmacological Review.
- Authors
Wang, Anqi; Lin, Ligen; Wang, Yitao
- Abstract
Penthorum chinense Pursh ( Ganhuangcao), a traditional Chinese medicine, is used for the prevention and treatment of liver diseases, including hepatitis B, hepatitis C, and alcoholic liver damage. A wide range of investigations have been carried out on this herbal medicine from pharmacognosy to pharmaceuticals, as well as pharmacology. The extract of P. chinense was reported to have significant liver protective effects through anti-oxidation, reduction of key enzyme levels, inhibition of hepatitis B virus DNA replication, and promotion of bile secretion. Based on the current knowledge, flavonoids and phenols are considered to be responsible for P. chinense's bioactivities. The main purpose of this review is to provide comprehensive and up-to-date knowledge of the phytochemical and pharmacological studies performed on P. chinense during the past few decades. Moreover, it intends to provide new insights into the research and development of this herbal medicine.
- Subjects
THERAPEUTIC use of plant extracts; PHYTOCHEMICALS; ANTIOXIDANTS; BILE; ANALYTICAL chemistry; FLAVONOIDS; HEPATITIS; HEPATITIS viruses; LIVER diseases; BOTANIC medicine; CHINESE medicine; MOLECULAR structure; PHARMACOLOGY; POLYPHENOLS; THERAPEUTICS
- Publication
American Journal of Chinese Medicine, 2015, Vol 43, Issue 4, p601
- ISSN
0192-415X
- Publication type
Article
- DOI
10.1142/S0192415X15500378