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- Title
An unusual radiological manifestation in osmotic demyelination syndrome.
- Authors
Rajitha, D.; Sunil, E.; Kumar, P. Satish; Nagasuresh, M.; Rajagopal, G.; Suresh, V.; Vengamma, B.; Devi, B. Vijayalaxmi; Laxmi, A. Y.; Sachan, Alok
- Abstract
Introduction: Too rapid correction of hyponatremia leads to serious neurological complications, like osmotic demyelination syndrome (ODS). Imaging shows features of pontine myelinolysis, sometimes isolated and associated with extrapontine myelinolysis. Isolated extrapontine myelinolysis is extremely rare. Aim and Objectives: We describe a case of ODS with unusual radiological findings. Case Report: A 53-year-old female was brought to the emergency services with vomiting and altered sensorium. Patient had profound hyponatremia (110 meq/l). Correction was done with slow intravenous infusion of 3% NaCl. However, unmonitored oral administration of salt led to overcorrection with serum sodium of 150 meq/l. She developed quadriplegia, depressed level of consciousness and respiratory failure and required ventilatory support. MRI brain showed features of isolated extrapontine myelinolysis.
- Subjects
DEMYELINATION; HYPONATREMIA; SYMPTOMS; INTRAVENOUS therapy; MAGNETIC resonance imaging of the brain
- Publication
Indian Journal of Endocrinology & Metabolism, 2012, Vol 16, pS522
- ISSN
2230-8210
- Publication type
Case Study