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- Title
The value of S-Detect in improving the diagnostic performance of radiologists for the differential diagnosis of thyroid nodules.
- Authors
Qi Wei; Shu-E Zeng; Li-Ping Wang; Yu-Jing Yan; Ting Wang; Jian-Wei Xu; Meng-Yi Zhang; Wen-Zhi Lv; Xin-Wu Cui; Dietrich, Christoph F.; Wei, Qi; Zeng, Shu-E; Wang, Li-Ping; Yan, Yu-Jing; Wang, Ting; Xu, Jian-Wei; Zhang, Meng-Yi; Lv, Wen-Zhi; Cui, Xin-Wu
- Abstract
<bold>Aims: </bold>To compare the diagnostic value of S-Detect (a computer aided diagnosis system using deep learning) in differentiating thyroid nodules in radiologists with different experience and to assess if S-Detect can improve the diagnostic performance of radiologists.<bold>Materials and Methods: </bold>Between February 2018 and October 2019, 204 thyroid nodules in 181 patients were included. An experienced radiologist performed ultrasound for thyroid nodules and obtained the result of S-Detect. Four radiologists with different experience on thyroid ultrasound (Radiologist 1, 2, 3, 4 with 1, 4, 9, 20 years, respectively) analyzed the conventional ultrasound images of each thyroid nodule and made a diagnosis of "benign" or "malignant" based on the TI-RADS category. After referring to S-Detect results, they re-evaluated the diagnoses. The diagnostic performance of radiologists was analyzed before and after referring to the results of S-Detect.<bold>Results: </bold>The accuracy, sensitivity, specificity, positive predictive value and negative predictive value of S-Detect were 77.0, 91.3, 65.2, 68.3 and 90.1%, respectively. In comparison with the less experienced radiologists (radiologist 1 and 2), S-Detect had a higher area under receiver operating characteristic curve (AUC), accuracy and specificity (p <0.05). In comparison with the most experienced radiologist, the diagnostic accuracy and AUC were lower (p<0.05). In the less experienced radiologists, the diagnostic accuracy, specificity and AUC were significantly improved when combined with S-Detect (p<0.05), but not for experienced radiologists (radiologist 3 and 4) (p>0.05).<bold>Conclusions: </bold>S-Detect may become an additional diagnostic method for the diagnosis of thyroid nodules and improve the diagnostic performance of less experienced radiologists.
- Subjects
NODULAR disease; THYROID nodules; RADIOLOGISTS; RECEIVER operating characteristic curves; DIFFERENTIAL diagnosis
- Publication
Medical Ultrasonography, 2020, Vol 22, Issue 4, p415
- ISSN
1844-4172
- Publication type
journal article
- DOI
10.11152/mu-2501