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- Title
Week-to-week within-subject and between-subject biological variation of copeptin.
- Authors
Guldhaug, Nora Alicia; Røys, Eirik Åsen; Viste, Kristin; Thorsby, Per Medbøe; Sylte, Marit Sverresdotter; Torsvik, Janniche; Strand, Heidi; Alaour, Bashir; Marber, Michael; Omland, Torbjørn; Aakre, Kristin Moberg
- Abstract
This document presents the findings of two studies on the biological variation of copeptin, a hormone associated with fluid imbalance and various physiological processes. The first study focused on establishing the week-to-week biological variation of copeptin using statistical methods. The results provide important information for interpreting test results and calculating reference values. The second study compared copeptin variation between different groups and suggested using delta values for clinical changes. Both studies acknowledge limitations and recommend further research. Overall, these studies contribute to our understanding of copeptin variation and its clinical implications.
- Subjects
BIOLOGICAL variation; OUTLIER detection; INAPPROPRIATE ADH syndrome
- Publication
Clinical Chemistry & Laboratory Medicine, 2024, Vol 62, Issue 2, pe29
- ISSN
1434-6621
- Publication type
Article
- DOI
10.1515/cclm-2023-0673