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- Title
Point prevalence survey of antibiotic use in hospitals in Latin American countries.
- Authors
Hara, Gabriel Levy; Rojas-Cortés, Robin; León, Helvert Felipe Molina; Mansilla, Anahí Dreser; Orta, Ismary Alfonso; Rizo-Amezquita, José Noe; Herrera, René Guillermo Santos; Ayala, Silvia Mendoza de; Villalobos, Marlen Arce; Ponte, Hilda Mantilla; Davila, Ever; Aguilar, Gloria; Porrás, Analía; Ramón-Pardo, Pilar; Castro, José Luis; Group, on behalf of the Latin American Point Prevalent Survey Study; Levy Hara, Gabriel; Molina León, Helvert Felipe; Dreser Mansilla, Anahí; Alfonso Orta, Ismary
- Abstract
<bold>Background: </bold>Point prevalence surveys (PPSs) on antibiotic use are useful for understanding different aspects related to prescription patterns in hospitals.<bold>Methods: </bold>An adaptation of the WHO methodology for a PPS on antibiotic use was applied. Hospital wards were divided into medical (MED), surgical (SUR), ICUs, gynaecology and obstetrics (GO), high-risk (HR) and mixed wards (MIX). A web application (RedCap©) through a mobile device was used for data collection.<bold>Results: </bold>Between December 2018 and August 2019, 5444 patients in 33 hospitals in five countries were included (10 hospitals in Cuba, 7 in Paraguay, 6 in El Salvador, 5 in Mexico and 5 in Peru). Of these patients, 54.6% received at least one antibiotic, with variations between and within hospitals and countries. Antibiotics were more frequently used in ICUs (67.2%), SUR (64.5%) and MED wards (54.2%), with 51.2% of antibiotics prescribed for community-acquired infections (CAIs), 22.9% for healthcare-associated infections (HAIs), 11.1% for surgical prophylaxis and 6.1% for unknown reasons. Adherence to guidelines was observed in 68.6% of cases (72.8% for CAIs, 72.4% for HAIs and 44.3% for prophylaxis). Third-generation cephalosporins were the class of antibiotics most frequently used (26.8%), followed by carbapenems (10.3%) and fluoroquinolones (8%). Targeted treatments were achieved in 17.3% of cases.<bold>Conclusions: </bold>Antibiotic use was generally higher than that published in other studies. There is an urgent need to promote and strengthen the antimicrobial stewardship programmes in Latin America.
- Subjects
EL Salvador; PARAGUAY; CUBA; LATIN America; HOSPITAL utilization; HOSPITAL wards; COMMUNITY-acquired infections; CARBAPENEMS; WEB-based user interfaces; INTENSIVE care units; ANTIBIOTICS; CEFAZOLIN; HOSPITALS; RESEARCH; RESEARCH methodology; CROSS infection; EVALUATION research; COMPARATIVE studies; DISEASE prevalence
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2022, Vol 77, Issue 3, p807
- ISSN
0305-7453
- Publication type
journal article
- DOI
10.1093/jac/dkab459