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- Title
BRAF<sup>V600E</sup> expression in ameloblastomas: Report of two cases.
- Authors
da Mota Santana, Lucas Alves; Cunha, John Lennon Silva; de Oliveira, Eduardo Morato; Sabey, Mark John Santana; Rezende‐Silva, Erika; de Almeida Souza, Liane Maciel; Trento, Cleverson Luciano
- Abstract
Genetic study of the BRAF gene reveals new variants and high frequency of the V600E mutation among Iranian ameloblastoma patients. Ameloblastoma is one of the most common odontogenic tumours corresponding to about 11% of neoplasms of this group.1 Despite its benign nature, this tumour presents aggressive behaviour, with significant destruction of the maxillary bones, and high rates of recurrence.2 Although its clinical-radiographical and morphological characteristics are well-established in the literature, its pathogenesis remains poorly understood.
- Subjects
AMELOBLASTOMA; MITOGEN-activated protein kinases
- Publication
Oral Surgery (1752-2471), 2022, Vol 15, Issue 3, p467
- ISSN
1752-2471
- Publication type
Article
- DOI
10.1111/ors.12586