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- Title
Hepatic Decompensation in Patients With HIV/Hepatitis B Virus (HBV)/Hepatitis C Virus (HCV) Triple Infection Versus HIV/HCV Coinfection and the Effect of Anti-HBV Nucleos(t)ide Therapy.
- Authors
Lo Re, Vincent; Wang, Li; Devine, Scott; Baser, Onur; Olufade, Temitope
- Abstract
The incidence rate of hepatic decompensation was higher in patients with human immunodeficiency virus (HIV)/hepatitis B virus (HBV)/hepatitis C virus (HCV) triple infection than in those with HIV/HCV coinfection (24.1 vs 10.8 events per 1000 person-years; hazard ratio [HR], 1.89; 95% confidence interval [CI], 1.12–3.18). Compared with HIV/HCV-infected patients, the rate of decompensation was increased among HIV/HBV/HCV-infected patients receiving no anti-HBV therapy (HR, 2.48; 95% CI, 1.37–4.49) but not among those who did receive such therapy (HR, 1.09; 95% CI, .40–2.97)
- Subjects
HEPATITIS B virus; HIV-positive persons; HEPATITIS C virus; VIRAL vaccines; CONFIDENCE intervals; PATIENTS
- Publication
Clinical Infectious Diseases, 2014, Vol 59, Issue 7, p1027
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciu476