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- Title
Effect of Acupressure on Fatigue in Hemodialysis Patients: A Single-Blinded Randomized Controlled Trial.
- Authors
Suandika, Made; Chen, Shih-Ying; Fang, Ji-Tseng; Yang, Sien-Hung; Tsai, Yun-Fang; Weng, Li-Chueh; Tsay, Pei-Kwei; Tang, Woung-Ru
- Abstract
Objectives: The objective of this study was to investigate the effect of acupressure on fatigue severity, sleep quality, and psychological status in patients with end-stage renal disease (ESRD) receiving hemodialysis (HD) treatment. Design: A single-blinded parallel-group randomized controlled trial. Settings/Location: A medical center in central Java, Indonesia. Subjects: One hundred and six patients who had been receiving HD for at least 3 months were enrolled in this study and randomly assigned to two groups. Interventions: The experimental group received acupressure at K1, ST36, and SP6 acupoints. In contrast, the control group received sham acupressure at 1 cun from these three acupoints. Subjects received acupressure thrice per week for 4 weeks, and pressure on each acupoint was applied for 3 min bilaterally. Outcome measures: The primary outcome was fatigue severity, while sleep quality and psychological status (depression/anxiety) were evaluated as secondary outcomes. Outcomes were assessed using the Brief Fatigue Inventory, Pittsburgh Sleep Quality Index, and Hospital Anxiety and Depression Scale. Results: Acupressure induced a significant medium to large effect on improvement in fatigue (b = −1.71, confidence interval [95% CI]: −1.90 to −1.51, ΔR2 = 0.744), sleep quality (b = −5.81, 95% CI: −6.80 to −4.81, ΔR2 = 0.525), and anxiety (Estimate = −3.213, 95% CI: −4.238 to −2.188, pseudo R2 = 0.292)/depression (Estimate = −3.378, 95% CI: −4.432 to −2.325, pseudo R2 = 0.268) in experimental group patients compared to controls. No adverse events of acupressure were reported during the study process. Conclusions: Acupressure significantly and independently improved fatigue, depression/anxiety, and sleep quality in ESRD patients receiving HD. Clinical Trial Registration: NCT05571007
- Subjects
INDONESIA; ANXIETY treatment; CHRONIC kidney failure; SLEEP quality; STATISTICAL power analysis; CONFIDENCE intervals; MULTIPLE regression analysis; ACUPRESSURE; HEMODIALYSIS patients; TREATMENT effectiveness; RANDOMIZED controlled trials; PSYCHOSOCIAL factors; MENTAL depression; BLIND experiment; DESCRIPTIVE statistics; QUESTIONNAIRES; ACUPUNCTURE points; FATIGUE (Physiology); STATISTICAL sampling; DATA analysis software
- Publication
Journal of Integrative & Complementary Medicine, 2023, Vol 29, Issue 2, p111
- ISSN
2768-3605
- Publication type
Article
- DOI
10.1089/jicm.2022.0644