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- Title
Mycobacteraemia among HIV-1-infected patients in São Paulo, Brazil: 1995 to 1998.
- Authors
Hadad DJ; Palaci M; Pignatari ACC; Lewi DS; Machado MAS; Telles MAS; Martins MC; Ueki SYM; Vasconcelos GM; Palhares MCA; Hadad, D J; Palaci, M; Pignatari, A C C; Lewi, D S; Machado, M A S; Telles, M A S; Martins, M C; Ueki, S Y M; Vasconcelos, G M; Palhares, M C A
- Abstract
From July 1995 to August 1998, mycobacterial blood cultures were obtained from 1032 HIV-infected patients seen at the Centro de Referência e Treinamento de AIDS (CRTA), Hospital São Paulo (HSP), and Centro de Referência de AIDS de Santos (CRAS). Overall, 179 episodes of mycobacteraemia were detected: 111 (62.0%) at CRTA, 50 (27.9%) at HSP, and 18 (10.1%) at CRAS. The frequency of positive cultures declined sharply from 22.6% in 1995 to 6.9% in 1998, consistent with the decrease in opportunistic infections following the publicly funded distribution of highly active antiretroviral therapy. In 1995, mycobacteraemia was more frequently due to Mycobacterium avium complex (59.2%) than Mycobacterium tuberculosis (28.6%), whereas in 1998 the relative frequencies were reversed (28.6 vs. 64.3% respectively), probably justified by the increased virulence of M. tuberculosis and the greater risk of invasive infection in less-immunocompromised patients, including patients unaware they are infected with HIV.
- Publication
Epidemiology & Infection, 2004, Vol 132, Issue 1, p151
- ISSN
0950-2688
- Publication type
journal article
- DOI
10.1017/s0950268803001535