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- Title
Graves' disease with anti-GQ1b antibody syndrome: a rare case report.
- Authors
Liang, Tao; Zhou, Zhiwei; Hu, Xiaolin; Luo, Zhong
- Abstract
<bold>Background: </bold>Graves' disease and anti-GQ1b antibody syndrome are both autoimmune diseases, and there have been few reports on whether there is a correlation between the two. In this study, we present the case of a woman who was diagnosed with Graves' disease and anti-GQ1b antibody syndrome in succession.<bold>Case Presentation: </bold>The chief complaints of this patient were limb weakness and blurred vision. Graves' disease was diagnosed by examination of thyroid function and thyroid autoantibodies, but the clinical symptoms were not relieved after antihyperthyroidism treatment. Finally, it was found that Graves' disease was complicated by anti-GQ1b antibody syndrome, and the symptoms were relieved after treatment with glucocorticoids and intravenous immunoglobulin. We also explored the possible mechanism of these diseases through a literature review.<bold>Conclusions: </bold>We report a rare case of the cooccurrence of Graves' disease and anti-GQ1b antibody syndrome. Immune dysregulation might be the pathogenesis of the association, but there is no precise supporting evidence, and more research is needed.
- Subjects
THYROID diseases; IMMUNOGLOBULINS; AUTOIMMUNE diseases; SYMPTOMS; AUTOANTIBODIES; SYNDROMES; LITERATURE reviews
- Publication
BMC Neurology, 2021, Vol 21, Issue 1, p1
- ISSN
1471-2377
- Publication type
journal article
- DOI
10.1186/s12883-021-02245-1