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- Title
Comparison of Adverse Effects of COVID-19 Vaccines Among Elderly: Pfizer/BioNTech Versus CoronaVac.
- Authors
Evren, Hakan; Evren, Emine Ünal; Barış, Serap Argun; İnce, Figen Gülen; Soydan, Cenk; Elçi, Ömür Çınar; Yıldız, Füsun
- Abstract
Purpose: The SARS-CoV-2 infection has triggered the COVID-19 pandemic with enormous public health and economic consequences. The safety and efficacy of currently available COVID-19 vaccines have been demonstrated in few studies; however, further information on specific high-risk groups like the elderly with comorbidities is needed. In this crosssectional study, we aimed to compare the adverse side effects of two different COVID-19 vaccines (RNA-based Pfizer/BioNTech and inactivated CoronaVac) among the elderly with comorbidities. Methods: We selected a total of 800 participants 65 years or older from Turkish Republic of Northern Cyprus who received either one of the vaccines. We collected data on the possible side effects that have been previously attributed to coronavirus vaccination via quantitative telephone interviews. Results: We found that both CoronaVac and Pfizer/BioNTech were safe in adults over 65 years old, even with comorbidities. The most common side effects were pain on the injection site and fatigue. Adverse effects, particularly allergic reactions, were higher in Pfizer/BioNTech vaccinated group compared with the CoronaVac group. Conclusion: In conclusion, both vaccines were well tolerated and safe among the elderly even with comorbidities, As this specific group was largely excluded from the previous trials, we believe that this study may have a contributing impact on vaccine acceptance and health policy decision-making.
- Subjects
COVID-19 vaccines; ADVERSE health care events; OLDER people; BIONTECH SE; PFIZER Inc.; VACCINE effectiveness
- Publication
Acibadem Saglik Bilimleri Dergisi, 2023, Vol 14, Issue 3, p353
- ISSN
1309-470X
- Publication type
Article
- DOI
10.31067/acusaglik.1076933