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- Title
The relationship between dietary inflammatory index and bone mineral density in CKD patients.
- Authors
Wu, Wenhui; Li, Xiurong; Di, Jia; Zhou, Hua; Niu, Hongyan; Chen, Lu; Sha, Qi; Yang, Min
- Abstract
Introduction: Chronic systemic inflammation was proposed as a critical factor in the development of osteoporosis. We aim to investigate the effect of the DII on bone mineral density (BMD) in CKD patients. Methods: 2276 participants from NHANES were enrolled. The DII score was calculated based on a single 24‐h dietary recall. Total BMD was measured using Dual‐energy x‐ray absorptiometry. A multiple‐stepwise linear regression model was used to determine associations between BMD and DII in CKD patients. Results: When DII >0.35, a negative correlation was obtained between DII and BMD (all β = −0.008 and p < 0.05). In subgroup analysis, BMD levels decreased across increasing tertiles of the DII for patients with non‐osteoporosis, postmenopause, and low eGFR (p for trend ≤0.01). Conclusion: Higher consumption of pro‐inflammatory diet correlates negatively with the BMD levels in CKD patients.
- Subjects
BONE density; DUAL-energy X-ray absorptiometry; CHRONIC kidney failure; OSTEOPOROSIS
- Publication
Therapeutic Apheresis & Dialysis, 2024, Vol 28, Issue 1, p69
- ISSN
1744-9979
- Publication type
Article
- DOI
10.1111/1744-9987.14063