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- Title
Unlocking the secrets of the genome.
- Authors
Celniker, Susan E.; Dillon, Laura A. L.; Gerstein, Mark B.; Gunsalus, Kristin C.; Henikoff, Steven; Karpen, Gary H.; Kellis, Manolis; Lai, Eric C.; Lieb, Jason D.; MacAlpine, David M.; Micklem, Gos; Piano, Fabio; Snyder, Michael; Stein, Lincoln; White, Kevin P.; Waterston, Robert H.
- Abstract
The article focuses on the Encyclopedia of DNA Elements (modENCODE) project launched by the U.S. National Human Genome Research Institute (NHGRI) in 2003. It states that project, which aims to define the functional elements in the human genome, uses the genomes of species Caenorhabditis elegans and Drosophila melanogaster to determine how genetic information produces complex organism. The article also discusses the scientific perspectives offered by modENCODE and explains the fact that C. elegans and D. melanogaster will become ideal models DNA-based functional elements on a genome wide basis.
- Subjects
UNITED States; HUMAN genome; NATIONAL Human Genome Research Institute (U.S.); CAENORHABDITIS elegans; DROSOPHILA melanogaster; ANIMAL models in research; ANIMAL species; LABORATORY animals; PROJECT management
- Publication
Nature, 2009, Vol 459, Issue 7249, p927
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/459927a