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- Title
Persistence of long-term insulin independence after islet transplantation and two subsequent pregnancies.
- Authors
Gondek, Sarah; Ogledzinski, Mateusz; Lin, William; Milejczyk, Kamila; Juengel, Braden; Potter, Lisa; Bachul, Piotr J.; Basto, Lindsay; Perea, Laurencia; Ling-Jia Wang; Tibudan, Martin; Witkowska, Zuzanna; Barth, Rolf; John Fung; Witkowski, Piotr
- Abstract
Pregnancy increases metabolic demand for insulin and may lead to the exhaustion of intraportally transplanted islets and post-gestational hyperglycemia. To prevent these complications, we implemented preemptive insulin supplementation during two subsequent pregnancies in an insulin-independent islet transplant recipient. This strategy resulted in optimal blood glucose control during the pregnancies, the preservation of the optimal islet graft function and the postpartum maintenance of long-term insulin independence.
- Subjects
INSULIN; HYPERGLYCEMIA; ISLANDS of Langerhans transplantation; PREGNANCY complications; BLOOD sugar
- Publication
European Journal of Translational & Clinical Medicine, 2023, Vol 6, Issue 1, p9
- ISSN
2657-3148
- Publication type
Article
- DOI
10.31373/ejtcm/166178