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- Title
The Relationship between ACE , ACTN3 and MCT1 Genetic Polymorphisms and Athletic Performance in Elite Rugby Union Players: A Preliminary Study.
- Authors
Pasqualetti, Massimo; Onori, Maria Elisabetta; Canu, Giulia; Moretti, Giacomo; Minucci, Angelo; Baroni, Silvia; Mordente, Alvaro; Urbani, Andrea; Galvani, Christel
- Abstract
Athletic performance is influenced by many factors such as the environment, diet, training and endurance or speed in physical effort and by genetic predisposition. Just a few studies have analyzed the impact of genotypes on physical performance in rugby. The aim of this study was to verify the modulation of genetic influence on rugby-specific physical performance. Twenty-seven elite rugby union players were involved in the study during the in-season phase. Molecular genotyping was performed for: angiotensin-converting enzyme (ACE rs4646994), alfa-actinin-3 (ACTN3 rs1815739) and monocarboxylate transporter 1 (MCT1 rs1049434) and their variants. Lean mass index (from skinfolds), lower-limb explosive power (countermovement jump), agility (505), speed (20 m), maximal aerobic power (Yo-yo intermittent recovery test level 1) and repeated sprint ability (12 × 20 m) were evaluated. In our rugby union players ACE and ACTN3 variants did not show any influence on athletic performance. MCT1 analysis showed that TT-variant players had the highest peak vertical power (p = 0.037) while the ones with the AA genotype were the fastest in both agility and sprint tests (p = 0.006 and p = 0.012, respectively). Considering the T-dominant model, the AA genotype remains the fastest in both tests (agility: p = 0.013, speed: p = 0.017). Only the MCT1 rs1049434 A allele seems to be advantageous for elite rugby union players, particularly when power and speed are required.
- Subjects
ELITE athletes; RUGBY football players; ATHLETIC ability; AEROBIC capacity; MONOCARBOXYLATE transporters; GENETIC polymorphisms; ANGIOTENSIN converting enzyme
- Publication
Genes, 2022, Vol 13, Issue 6, p969
- ISSN
2073-4425
- Publication type
Article
- DOI
10.3390/genes13060969